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costus pictus/necrosis

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Insulin Plant (Costus pictus) Extract Restores Thyroid Hormone Levels in Experimental Hypothyroidism.

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BACKGROUND The aim of the present study was to investigate the preventive effect of Costus pictus leaf extract in experimental hypothyroidism. METHODS Forty male Wistar rats were randomly divided into four groups with ten rats in each group: Control (C), hypothyroid (H), control+extract (C+E), and

Costunolide inhibits proinflammatory cytokines and iNOS in activated murine BV2 microglia.

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Costunolide, a sesquiterpene lactone present in Costus speciosus root exerts a variety of pharmacological activity but its effects on neuroinflammation have not been studied. Microglia, the resident phagocytic cells in the central nervous system respond to neuroinflammation and their overwhelming
Ethnopharmacological relevance: Costus spicatus (Jacq.) Sw., also known as "cana-do-brejo," is a species that is widely used in Brazilian traditional medicine for the treatment of kidney diseases. However, no studies have evaluated its

The effects of subinhibitory concentrations of costus oil on virulence factor production in Staphylococcus aureus.

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OBJECTIVE To determine the antimicrobial activity of costus (Saussurea lappa) oil against Staphylococcus aureus, and to evaluate the influence of subinhibitory concentrations of costus oil on virulence-related exoprotein production in staph. aureus. RESULTS Minimal inhibitory concentrations (MICs)
BACKGROUND Rheumatoid arthritis (RA) is a systemic autoimmune disorder characterized by polyarticular symmetrical arthritis. The prevalence of RA is consistent worldwide, affecting about 0.5%-1.0% of the population. The aim of this study was to investigate whether Saussurea lappa (costus) could
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