dextrose/hypoxia

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Dextrose-, adenosine- and magnesium-induced protective actions during anoxia and reperfusion in canine Purkinje tissue.

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1. The effects of dextrose, magnesium (Mg) and adenosine on membrane potential and force of contraction were studied in driven and overdriven canine cardiac Purkinje tissue. 2. Dextrose (50 mmol/L) and adenosine (4-6 mmol/L) both showed protective action (the latter to a lesser extent) against

Effects of dextrose, verapamil and magnesium during hypoxia in myocardial tissue.

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We studied the effects of superfusion of canine heart muscle tissue with a solution that mimicks hypoxia, acidosis and hyperkalemia (altered Tyrode's solution). Contracture (rise in resting tension) develops much sooner (5.2 +/- 0.8 vs. 30-40 min in 5 mM dextrose) in the absence of dextrose. High

The effects of operation, anoxia and the postoperative administration of dextrose and water upon tissue electrolytes as revealed by analyses of muscle biopsies.

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Blood sugar and dextrose tolerance during anoxia in the dog.

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Hypoxia causes glucose intolerance in humans.

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Hypoxic respiratory diseases are frequently accompanied by glucose intolerance. We examined whether hypoxia is a cause of glucose intolerance in healthy subjects. In a double-blind within-subject crossover design, hypoxic versus normoxic conditions were induced in 14 healthy men for 30 minutes by

Transient anoxia during Metarhizium robertsii growth increases conidial virulence to Tenebrio molitor.

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Little is known about the phenotypic effects of hypoxia and transient anoxia on the virulence of an entomopathogenic fungus. Conidia of Metarhizium robertsii were produced on: (1) potato dextrose agar medium (PDA) under normoxia; (2) PDA medium under continuous hypoxia; (3) PDA medium under

Liver hypoxia and lack of recovery after reperfusion at high blood alcohol levels in the intragastric feeding model of alcohol liver disease.

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The purpose of this study was to test for the presence of liver hypoxia and recovery after reperfusion when blood alcohol levels (BAL) are high. Male rats were fed ethanol intragastrically at a constant rate for 1 month. The pO(2) levels were then measured on the liver surface of these rats, in vivo

Hypoxemia and hypercapnia in conscious dogs: opioid modulation of catecholamines.

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The role of endogenous opioids in systemic and renal circulatory changes during combined acute hypoxemia and hypercapnic acidosis was evaluated in seven conscious female mongrel dogs in rigid sodium balance. Animals were studied 2 wk apart in separate protocols of combined acute hypoxemia (arterial

Factors controlling aldosterone secretion during hypoxemia in fetal lambs.

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Factors modulating the fetal aldosterone response to hypoxemia were studied in three groups of chronically catheterized fetal lambs between 131 and 143 days of gestation (term, 145 days). One group (control group) received an infusion of 5% dextrose in water; the second group (captopril-treated

Effect of amino acid infusion on the ventilatory response to hypoxia in protein-deprived neonatal piglets.

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Several amino acids (AA) act as neurotransmitters and mediate the ventilatory response to carbon dioxide and hypoxia in adult human beings and animals. To evaluate the influence of AA on the neonatal ventilatory response to hypoxia, 29 newborn piglets less than 5 d old were randomly assigned to a

Effect of L-aspartate on the ventilatory response to hypoxia in sedated newborn piglets.

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L-aspartate (L-ASP) acts as an excitatory amino acid neurotransmitter at the synapses of brain stem respiratory neurons. In order to determine the effect of L-ASP on the neonatal ventilatory response to hypoxia, 9 control piglets [age 4.3 +/- (SD) 0.9 days, weight 1.9 +/- 0.5 kg] and 9 L-ASP-treated

Effects of hypoxemia on gastrointestinal blood flow and gastric emptying in the newborn piglet.

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The effects of severe hypoxemia on gastrointestinal (GI) blood flow and gastric emptying were studied in nine 2- to 4-day-old piglets which were mechanically ventilated while receiving nitrous oxide anesthesia. Each animal was studied during a control period of oxygenation (PaO2 91 +/- 8 torr), 35

The effect of dextrose and amino acids on respiratory function and energy expenditure in morbidly obese patients following gastric bypass surgery.

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Hypocaloric dextrose administration results in a diminished minute ventilation, metabolic rate, and ventilatory responsivity to hypercapnea and hypoxia which is rapidly reversed by provision of amino acids in individuals of normal weight. This study compared the effects of peripheral intravenous

Effects of hypoxia and azotaemia on the pharmacokinetics of amikacin in neonatal foals.

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The effects of hypoxia and azotaemia on the pharmacokinetics of amikacin were evaluated in 20 full-term neonatal critically ill foals which required 24-h supportive care, antibiotics and dextrose-supplemented polyionic fluids given intravenously, nasal insufflation with oxygen and nutritional

Cardiac function during long-term hypoxemia in fetal sheep.

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To examine right ventricular function during long-term hypoxemia, we instrumented 12 fetal sheep with intravascular catheters and an electromagnetic flow probe on the pulmonary artery. In six cases, hypoxemia was induced by infusing N2 gas into the maternal trachea for 2 wk. Maternal arterial PO2

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