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diabetes mellitus type 1/nicotine

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UNASSIGNED Youth with chronic conditions may engage in risky behaviour to the same, if not higher, degree as their healthy peers. UNASSIGNED To determine the prevalence of alcohol, tobacco, cannabis and illicit substance use in adolescents with type 1 diabetes (T1DM) compared to a general adolescent
It has been suggested that moist snuff (snus), a smokeless tobacco product that is high in nicotine and widespread in Scandinavia, increases the risk of Type 2 diabetes. Previous studies are however few, contradictory and, with regard to autoimmune diabetes, lacking. Our aim was to study the
Human placental lactogen (hPL) is a peptidic hormone that belongs to the short list of growth factors that could treat type-1 diabetes through pancreatic islet transplantation. Placental lactogen has the capacity to improve islet survival and function before or after transplantation. In this study,

Attenuated Tregs increase susceptibility to type 1 diabetes in prenatal nicotine exposed female offspring mice.

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The recession of regulatory T cells (Tregs) is pivotal for type 1 diabetes (T1D) progressing. Our previous study observed the decreased Tregs in prenatal nicotine exposure (PNE) offspring, but whether this led to the onset of T1D remains uncertain. Thus, this study aimed to investigate the effects

Tobacco smoking decreases clinical symptoms of gingivitis in patients with type 1 diabetes-a cross-sectional study.

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OBJECTIVE Periodontal disease may develop on the background of microvascular complications of diabetes. However, some modifying factors, such as tobacco smoking, should be taken into consideration when assessing risk of development of chronic complications. The aim of the study was the clinical
The effects of Type 1 diabetes mellitus and of exposure to mainstream cigarette smoke on noradrenaline (NA) uptake and its subsequent metabolism by catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO) in the perfused lungs of rats were examined. In diabetic (streptozotocin-treated) rats,
Thirty-four consecutive patients with diabetes mellitus as a plausible cause of end-stage renal failure were investigated with regard to outcome and tobacco consumption. The mean duration of diabetes was 25.5 years. Thirty-one of the patients had used tobacco regularly for at least 5 years. For 28

Acute Psychosis in Withdrawal from Nicotine Vaping in a Young Man with Comorbid Diabetic Ketoacidosis and Cannabis Use

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Electronic delivery of nicotine, also termed "vaping," has a growing evidence base suggesting potential harm through both exposure and withdrawal effects. The current report presents the case of a young man with multiple medical comorbidities, including insulin-dependent diabetes mellitus on an

Substance Use in Adults With Type 1 Diabetes in the T1D Exchange.

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OBJECTIVE The purpose of the study was to evaluate frequency of use and problem use of psychoactive substances in adults with type 1 diabetes (T1D). METHODS Standardized instruments for assessing tobacco, alcohol, and other psychoactive substance use were emailed to 4311 adult participants at 69 T1D
To survey adolescents with type 1 diabetes mellitus (T1DM) about their knowledge and application of harm-reduction recommendations when they engage in alcohol and other illicit substance use.Cross-sectional survey and chart review of adolescents with T1DM

Prenatal and postnatal tobacco smoke exposure and development of insulin resistance in 10 year old children.

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In this study, we evaluated the association between prenatal and postnatal exposure to environmental tobacco smoke and the development of insulin resistance in 10 year old children. Fasting blood samples were collected from 470 children participating in two prospective birth cohorts. Of those 276

A downstream process allowing the efficient isolation of a recombinant amphiphilic protein from tobacco leaves.

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The 65-kDa isoform of human glutamic acid decarboxylase (hGAD65) is a major autoantigen in autoimmune diabetes. The heterologous production of hGAD65 for diagnostic and therapeutic applications is hampered by low upstream productivity and the absence of a robust and efficient downstream process for

The influence of tobacco smoking on humoral immune response in insulin dependent diabetic pregnancy.

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Tobacco smoking products have a heavy impact on the public health of developed as well as non-developed countries by being a main etiologic factor for the induction of cardiovascular diseases and tobacco-related cancer. The purpose of this study was to determine the influence of tobacco smoking on

Warthin's tumour associated with autoimmune diseases and tobacco use.

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To better clarify the possible role of immune mechanisms in the pathogenesis of Warthin's tumour (WT), we performed a retrospective study of patients with WT surgically treated at the Institute of Otolaryngology Head and Neck Surgery, University of Florence, during a 25-year period; looking for a

Tobacco exposure and diabetes-related autoantibodies in children: results from the ABIS study.

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Passive smoking has decreased in recent years ("increased hygiene"). Less environmental tobacco smoke (ETS) gives increased hygiene that, if the hygiene hypothesis is true, in turn might give more autoimmune diseases. The presence of auto antibodies is considered to be an early indicator of type 1
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