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dicaffeoylquinic acid/infarction
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PK-PD Correlation of Erigeron Breviscapus Injection in the Treatment of Cerebral Ischemia-Reperfusion Injury Model Rats
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By measuring the cerebral infarction rate and neurological behavioral score of rats in a sham operation group, an MCAO model control group and an Erigeron breviscapus injection treatment group, we explored the therapeutic effects of Erigeron breviscapus injection on brain tissue and neuroethological
Caffeic acid ester fraction from Erigeron breviscapus inhibits microglial activation and provides neuroprotection.
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OBJECTIVE
To investigate the effects of caffeic acid ester fraction (Caf) from Erigeron breviscapus, mainly composed of dicaffeoylquinic acids (diCQAs), on microglial activation in vitro and focal cerebral ischemia in vivo.
METHODS
The production of nitric oxide (NO), tumor necrosis factor α
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