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epilepsy/fatigue

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FIELD OF THE INVENTION The present invention relates to transdermal devices and methods for controllable dispensing of a nutraceutical or an active substance such as a chemical substance, a medication, a drug, a stimulant or the like, to a human or other mammal for purposes of promoting longevity,
FIELD OF THE INVENTION The present invention relates to transdermal devices and methods for controllable dispensing of a nutraceutical or an active substance such as a chemical substance, a medication, a drug, a stimulant or the like, to a human or other mammal for purposes of promoting longevity,
FIELD OF THE INVENTION The present invention relates to transdermal devices and methods for controllable dispensing of a nutraceutical or an active substance such as a chemical substance, a medication, a drug, a stimulant or the like, to a human or other mammal for purposes of promoting longevity,
FIELD OF THE INVENTION The present invention relates to transdermal devices and methods for controllable dispensing of a nutraceutical or an active substance such as a chemical substance, a medication, a drug, a stimulant or the like, to a human or other mammal for purposes of promoting longevity,
FIELD OF THE INVENTION The present invention relates to transdermal devices and methods for controllable dispensing of a nutraceutical or an active substance such as a chemical substance, a medication, a drug, a stimulant or the like, to a human or other mammal for purposes of promoting longevity,

Indolin-2-one derivatives

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The present invention is concerned with indolin-2-one derivatives of general formula ##STR00002## wherein A is phenyl or a six membered heteroaryl group, containing one or two N atoms, selected from ##STR00003## or the amine group --NR.sup.1R.sup.2 may form together with two neighboring carbon atoms

Indolin-2-one derivatives

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The present invention is concerned with indolin-2-one derivatives of general formula ##STR00002## wherein A is phenyl or a five or six membered heteroaryl group, containing one or two N atoms, selected from ##STR00003## or the amide group --C(O)--NR.sup.1R.sup.2 may form together with two

Indolin-2-one derivatives

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The present invention is concerned with indolin-2-one derivatives of general formula ##STR00004## wherein A is phenyl or a six membered heteroaryl group, containing one or two N atoms, selected from ##STR00005## or the oxygen atom may form together with two neighboring carbon atoms from the group A

Indolin-2-one derivatives

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The present invention is concerned with indolin-2-one derivatives of general formula ##STR00004## wherein A is phenyl or a six membered heteroaryl group, containing one or two N atoms, selected from ##STR00005## R.sup.1 is S(O).sub.2lower alkyl, S(O).sub.2NR.sup.4R.sup.5, S(O).sub.2cycloalkyl,

Serotonin and norepinephrine reuptake inhibitors and uses thereof

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BACKGROUND OF THE INVENTION The market for neuroscience and women's health drugs has been moving towards the use of dual serotonin and norepinephrine reuptake inhibitors (SNRI) for first line treatment of various indications, as evidenced by the recent development of SNRI's such as Venlafaxine and

Serotonin and norepinephrine reuptake inhibitor and uses thereof

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BACKGROUND OF THE INVENTION The market for neuroscience and women's health drugs has been moving towards the use of dual serotonin and norepinephrine reuptake inhibitors (SNRI) for first line treatment of various indications, as evidenced by the recent development of SNRI's such as Venlafaxine and

Piperidine derivative

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CROSS REFERENCE TO RELATED APPLICATIONS This application is a U.S. National Phase application under 35 U.S.C. .sctn. 371 of PCT Application No. PCT/JP2004/013768, filed Sep. 21, 2004, which claims priority under 35 U.S.C. .sctn. 119 from Japanese Application No. JP2003-330758, filed Sep. 22,

Piperidine derivative

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TECHNICAL FIELD The present invention relates to a novel piperidine derivative, to a histamine-H3 receptor antagonist containing the novel piperidine derivative as an active ingredient thereof, and to a preventive or remedy for metabolic system diseases, circulatory system diseases, central or

Phenyl-substituted nicotinic ligands, and methods of use thereof

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BACKGROUND OF THE INVENTION Neuronal nicotinic acetylcholine receptors (nAChRs) serve a wide range of physiological functions and have been implicated in a number of pathological processes and pharmacological effects of nicotinic drugs. Many of the important in vivo effects of nicotine in the

Phenyl-substituted nicotinic ligands, and methods of use thereof

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BACKGROUND OF THE INVENTION Neuronal nicotinic acetylcholine receptors (nAChRs) serve a wide range of physiological functions and have been implicated in a number of pathological processes and pharmacological effects of nicotinic drugs. Many of the important in vivo effects of nicotine in the
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