epilepsy/hypoxia

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Piperidine compounds for treating anoxia, cerebral ischemia migraine or epilepsy

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The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, traumatic injury, ischemia, migraine and epilepsy. It is well known

Compositions containing and methods of using N-acyl-1H-aminoindenes

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Throughout this application, various references are identified by authors and full citation. Disclosure of these publications in their entireties are hereby incorporated by reference into this application to more fully describe the state of the art to which this invention pertains. BACKGROUND OF THE

Prodrug salts

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TECHNICAL FIELD Provided are novel prodrug salts of selective aquaporin inhibitors, e.g., of aquaporin-4 and/or aquaporin-2, of Formula I as described below, their use as pharmaceuticals and pharmaceutical compositions comprising them, and novel intermediates used in and novel processes for their

Prodrug salts

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Crystalline forms of tricyclic compound acid salt or hydrate thereof, and method for making thereof

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TECHNICAL FIELD The present disclosure relates to novel crystalline acid salts of a tricyclic derivative or a hydrate thereof, and a production method thereof. BACKGROUND Drugs administered orally show medicinal effects through absorption, distribution, metabolism or elimination, and the intrinsic

Systems, devices and methods for the treatment of neurological disorders and conditions

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TECHNICAL FIELD The present disclosure generally relates to cutaneous neurostimulator systems, devices and methods of using the same and more particularly relates to cutaneous neurostimulator systems, devices and methods for treating or promoting recovery from neurological disorders or conditions,

Systems, devices and methods for the treatment of neurological disorders and conditions

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Systems, devices and methods for the treatment of neurological disorders and conditions

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This application is also related to the following copending applications: U.S. application Ser. No. 12/898,685, entitled "Extracranial Implantable Devices, Systems and Methods for Treatment of Neuropsychiatric Disorders," filed on even date herewith with U.S. application Ser. No. 12/898,686,

Piperidine compounds and their preparation and use

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The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy. It is well known that accumulation of

Piperidine compounds and their preparation and use

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The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy. It is well known that accumulation of

Piperidine compounds and their preparation and use

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The present invention relate s to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy. It is well known that accumulation of

Substituted piperidine compounds and their use

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Piperidine compounds and pharmaceutical compositions thereof

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The present invention relates to therapeutically active piperidine compounds, a method of preparing the same, pharmaceutical compositions comprising the compounds and to a method of treating therewith. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy. It is

Piperidine compounds and their preparation and use

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The invention will now be described in further detail with reference to the following examples: Example 1 (-)-trans-4-(-4-fluorophenyl)-3-(3,4-methylenedioxyphenoxymethyl)-1-pentylp iperidine hydrochloride 10g of (-)-trans-4-(-4-fluorophenyl)-3,4-methylenedioxyphenoxymethyl)-piperidine hydrochloride

N,N'-disubstituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention is in the field of medicinal chemistry. In particular, this invention relates to N,N'-disubstituted guanidine analogues, and to compounds and pharmaceutical composition comprising the same, which possess neuroprotective capability. This invention further relates

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