epilepsy/nausea

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Recurrent nausea as part of the spectrum of abdominal epilepsy.

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Evaluation of JNJ-26489112 in patients with photosensitive epilepsy: a placebo-controlled, exploratory study.

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OBJECTIVE To evaluate the activity of JNJ-26489112 in patients with photosensitive epilepsy and determine the doses that result in reduction or complete suppression of the intermittent photic stimulation (IPS) induced photoparoxysmal-EEG response (PPR). METHODS In this multicenter, single-blind,

Bathing epilepsy: a video case of an autonomic seizure.

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A six-year-old Moroccan boy experienced nausea, paleness and oral automatisms after almost every shower. A clinical diagnosis of bathing epilepsy was assumed. A video-EEG recording was taken during and after a shower and confirmed ictal high voltage repetitive slow waves over the left temporal lobe.

Sodium valproate in the treatment of intractable seizure disorders: a clinical and electroencephalographic study.

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A 12-week study of clinical response, EEG changes and serum antiepileptic drug (AED) levels using sodium valproate (VAL) was undertaken. The study showed that VAL is a powerful adjunct in the treatment of intractable epilepsy. It was most effective in patients with generalized seizures, but no

Adverse reactions in blood donors with a history of seizures or epilepsy.

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BACKGROUND Individuals with epilepsy or seizure disorders are restricted from donating blood because of concern that they are prone to adverse donor reactions such as syncope and convulsions. A study evaluating whether that concern is warranted is reported. METHODS During a 2-year period beginning

Regulations prohibiting blood donation by individuals with seizures or epilepsy are not necessary.

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Throughout the world people who have epilepsy and seizures are prohibited from donating blood. These restrictions are based on the assumption that they are prone to adverse donor reactions, specifically, syncope and convulsions. We describe a study evaluating whether that concern is warranted.

The importance of drug adverse effects compared with seizure control for people with epilepsy: a discrete choice experiment.

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BACKGROUND Antiepileptic drugs (AEDs) have been shown to reduce the severity and frequency of seizures for most patients. However, many patients experience adverse effects in order to maintain seizure control. METHODS A stated preference discrete choice experiment (DCE) was used to explore the

Do children with benign rolandic epilepsy have a higher prevalence of migraine than those with other partial epilepsies or nonepilepsy controls?

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OBJECTIVE Prior studies have given conflicting data concerning the association of benign rolandic epilepsy of childhood (BREC) and migraine but were limited by lack of sensitive, diagnostic criteria for childhood migraine. By using revised International Headache Society (IHS-R) criteria, we compared

Development of focal chronic epilepsy following focal status epilepticus in adult patients.

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In several experimental models, status epilepticus (SE) leads to secondary brain hyperexcitability and epileptogenesis. In humans, such phenomena have been rarely demonstrated, particularly in cases of SE involving the neocortical structures. We report a 36 year old woman that presented partial SE

Role of reflexology and antiepileptic drugs in managing intractable epilepsy--a randomized controlled trial.

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BACKGROUND This report is based on the results of a randomized parallel controlled trial conducted to determine the efficacy of reflexology therapy in managing intractable epilepsy. METHODS Subjects who failed epilepsy surgery or were not candidates for epilepsy surgery or were non-responders of

Is the comorbidity of epilepsy and migraine due to a shared genetic susceptibility?

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We tested the hypothesis that the comorbidity of migraine and epilepsy results from a shared genetic susceptibility to the two disorders. We used semistructured telephone interviews to collect information on migraine and epilepsy in the families (parents, siblings, and offspring) of 1,967 adult

Long-term tolerability and efficacy of lamotrigine in pediatric patients with epilepsy.

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Accumulating data suggest that the antiepilepsy drug lamotrigine, which has been available for adult use for more than a decade, also confers broad-spectrum, well-tolerated control of epilepsy in children. The current study--the open-label continuation phase of several short-term clinical

Propofol-dexmedetomidine versus propofol-remifentanil conscious sedation for awake craniotomy during epilepsy surgery.

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BACKGROUND Conscious sedation during awake craniotomy requires balanced anesthesia technique to achieve optimum sedation and analgesia. This technique should be done without causing respiratory depression or loss of consciousness. The present study aimed at evaluating the effect of

Abdominal Epilepsy: A Rare Cause of Unexplained Abdominal Pain

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Abdominal epilepsy (AE) is a very rare diagnosis; it is considered to be a category of temporal lobe epilepsies and is more commonly a diagnosis of exclusion. Demographic presentation of AE is usually in the pediatric age group. However, there is recorded documentation of its occurrence even in

Safety of 25- and 50-mg capsules in the initiation of zonisamide therapy in patients with epilepsy: an uncontrolled, open-label study.

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OBJECTIVE This study was designed to assess the safety of 25- and 50-mg dosage strengths of zonisamide for initial titration in patients with epilepsy. METHODS This phase 3, multicenter, open-label, uncontrolled study conducted at 26 study sites in the United States included male and female patients

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