erectile dysfunction/vomiting

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Sildenafil (Viagra) in the treatment of male erectile dysfunction in Nairobi.

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OBJECTIVE To evaluate the effectiveness of sildenafil (Viagra) in the treatment of male erectile dysfunction in Nairobi. METHODS Prospective open label extension study. METHODS Urology clinics at the Nairobi Hospital, Kenyatta National Hospital and the author's private clinic in Hurlingham,

Comparative cross-over study of sildenafil and apomorphine for treating erectile dysfunction.

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OBJECTIVE To compare the effectiveness, safety and tolerability of sildenafil and apomorphine in Brazilian patients with erectile dysfunction (ED) of various causes. METHODS In all, 108 patients (mean age 55 years, sd 11) and documented ED for > or =6 months were included in 12 centres in Brazil.

Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction.

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A new class of agents with potential utility for the treatment of erectile dysfunction has been discovered, guided by the hypothesis that selective D4 agonists are erectogenic but devoid of the side effects typically associated with dopaminergic agents. The lead agent

Modulation of Dopaminergic Pathways to Treat Erectile Dysfunction.

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The currently recommended first-line treatments of erectile dysfunction (ED), phosphodiesterase type 5 inhibitors (PDE5i), for example sildenafil, are efficacious in many patients with ED of vascular origin, but this therapy is insufficient in approximately 30-40% of men with ED where there is also

[The clinical efficacy of epristeride in the treatment of benign prostatic hyperplasia].

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OBJECTIVE To estimate the clinical safety, efficacy of Epristeride in the treatment of benign prostatic hyperplasia (BPH). METHODS One hundred and fourty-one BPH patients, aged from 50 to 83 years old [(66.18 +/- 6.41) yr], were given Epristeride tablets 5 mg p.o., twice daily for 120 days. To

A review of formulation techniques that impact the disintegration and mechanical properties of oradispersible drug delivery technologies.

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The drug treatment of acute disorders such as neuropathic pain, migraines, insomnia, vomiting, allergic rhinitis or erectile dysfunction requires an immediate pharmacological effect that may be achieved through parenteral drug administration. However, the parenteral route is not always convenient

Microvascular arterial bypass surgery: long-term outcomes using validated instruments.

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OBJECTIVE Penile microarterial bypass surgery may be the only treatment capable of restoring normal erectile function without the necessity of chronic use of vasoactive medications or placement of a penile prosthesis. Lack of standardization in patient selection, hemodynamic evaluation, surgical

Diabetic autonomic neuropathy causing gall bladder dysfunction.

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OBJECTIVE The objective of the study was to study gall bladder volume in fasting and 45 minutes post-prandial, by real time ultrasound in healthy controls and diabetic patients with and without autonomic neuropathy and to compare them. METHODS Age, Sex and body mass index (BMI) matched 50 healthy

Atomoxetine tolerability in pediatric and adult patients receiving different dosing strategies.

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OBJECTIVE Examine how different dosing schedules and recent stimulant therapy effect incidence, time to onset, and duration of common treatment-emergent adverse events (TEAEs) during atomoxetine treatment. METHODS Post hoc analyses including safety data (open-ended questions) from 22 pediatric and 3

Levomilnacipran for major depressive disorder: a systematic review of the efficacy and safety profile for this newly approved antidepressant--what is the number needed to treat, number needed to harm and likelihood to be helped or harmed?

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OBJECTIVE To describe the efficacy and safety of levomilnacipran (extended-release capsules) for the treatment of major depressive disorder (MDD). METHODS The pivotal registration trials were accessed by querying http://www.ncbi.nlm.nih.gov/pubmed/, http://www.clinicaltrialsregister.eu and

[Quetiapine and anticholinergic drugs induced ischaemic colitis: A case study].

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BACKGROUND The aim of this paper is to underline the need for systematic monitoring of patients treated with anticholinergic antipsychotic drugs. We present the clinical history of a 34-year-old adult, treated with quetiapine in combination with other drugs with anticholinergic effects. METHODS A

Trazodone: properties and utility in multiple disorders.

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Trazodone is an established antidepressant that is prescribed frequently as an off-label hypnotic with wide acceptance among psychiatrists. Owing to its atypical mixed serotonergic and adrenolytic pharmacology, trazodone has been investigated in a number of disorders besides depression and insomnia,

Reservoir herniation as a complication of three-piece penile prosthesis insertion.

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OBJECTIVE To obtain data concerning the incidence and management of reservoir herniation in inflatable penile prosthesis surgery in a clinical investigation. Reservoir herniation after scrotal placement of inflatable penile prosthesis is an unusual complication, and a review of the published medical

[Therapeutic neglect omission of individual treatment of secondary defective developments].

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The increasing application of group psychotherapy involves the danger that secondary defective developments which cannot be cured within the group, will be neglected. For these, a specific psychotherapy is necessary and particularly urgent since these cases show a tendency towards becoming chronic.

[Progressive dysautonomia in hemangioblastoma in the region of the fourth ventricle].

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Tumors of the posterior fossa presenting orthostatic hypotension are rare and only nine cases have been reported so far. The locations of almost all these tumors were near the fourth ventricle and three of them were hemangioblastoma. A case of a tumor of the fourth ventricle showing autonomic

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