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Corn oil-induced changes in the dorsal root ganglia of rats.

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The effects of corn oil on rat dorsal root ganglia (DRG) were examined by both light and electron microscopy. Rats were fed corn oil via intubation 5 days per week for 7 weeks. No apparent morphological lesion was observed in the DRG by means of light microscopic examination. However, various

Behavioral disturbances and vestibular pathology following crotonitrile exposure in rats.

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The dinitrile compound 3,3'-iminodipropionitrile causes a number of toxic effects in sensory systems, including degeneration of the vestibular sensory hair cells, as well as a neurofilamentous pathology in motor and sensory neurons. The chemical also causes permanent changes in behavior. These were

Unilateral or bilateral vagotomy induces ovulation in both ovaries of rats with polycystic ovarian syndrome.

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BACKGROUND Injecting estradiol valerate (EV) to pre-pubertal or adult female rat results in effects similar to those observed in women with polycystic ovarian syndrome (PCOS). One of the mechanisms involved in PCOS development is the hyperactivity of the sympathetic nervous system. In EV-induced

Exaggeration of experimental hypertension in rats by contraceptive steroids (Enovid).

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The possibly additive pressor effects of contraceptive steroids were studied by treating hypertensive rats chronically with Enovid. Renal hypertensive rats were unaffected by drug treatment during the first 5 weeks, but, from the 6th to the 8th week, Enovid-treated rats had much higher systolic

Does oral contraceptive (Enovid) treatment enhance renal hypertension in rats by inducing sympathetic hyperactivity?

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One-kidney renal hypertension was induced in rats that had been given Enovid or corn oil by daily gavage for 5 weeks, and treatment was then continued postoperatively for 10 weeks more. Systolic pressures began to rise almost immediately after hypertension was induced, and from the 4th postoperative

In Adult Rats With Polycystic Ovarian Syndrome, Unilateral or Bilateral Vagotomy Modifies the Noradrenergic Concentration in the Ovaries and the Celiac Superior Mesenteric Ganglia in Different Ways.

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In rats with polycystic ovarian syndrome (PCOS) induced by estradiol valerate (EV) injection, sectioning of the vagus nerve in the juvenile stage restores ovulatory function, suggesting that the vagus nerve stimulates the onset and development of PCOS. We analyzed whether in adult rats, the role

Sulforaphane protects rodent retinas against ischemia-reperfusion injury through the activation of the Nrf2/HO-1 antioxidant pathway.

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Retinal ischemia-reperfusion (I/R) injury induces oxidative stress, leukocyte infiltration, and neuronal cell death. Sulforaphane (SF), which can be obtained in cruciferous vegetables such as broccoli, exerts protective effects in response to oxidative stress in various tissues. These effects can be

Hearing loss following exposure during development to polychlorinated biphenyls: a cochlear site of action.

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Maternal exposure to polyhalogenated hydrocarbons results in early postnatal hypothyroxenemia and a low-frequency hearing loss in adult offspring (Goldey et al., 1995a. Toxicol. Appl. Pharmacol. 135, 67-76; Herr et al., 1996. Fundam. Appl. Toxicol. 33, 120-128). The purpose of the present work was

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