geraniol/hypersensitivity

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Contact allergy to fragrances: frequencies of sensitization from 1996 to 2002. Results of the IVDK*.

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Increasing frequencies of sensitization to the fragrance mix (FM) have been acknowledged as a serious problem for many years. It is well known that the single compounds (SCs) of the FM contribute differently to the FM patch rest reactions. In this study, we were interested in the time trends of the

Hydrogel allergic contact dermatitis and imidazolidinyl urea/diazolidinyl urea.

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Hydrogels contain modified carboxymethylcellulose polymer together with propylene glycol as known components. Nowadays, they are common agents used in the treatment of leg ulcer patients, and a possible cause of allergic contact dermatitis. However in the published data, not all the patients with

Contact allergy caused by fragrance mix and Myroxylon pereirae (balsam of Peru)--a retrospective study.

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Because of their widespread use, fragrances are among the most common causes of contact allergic dermatitis, second only to nickel. During a five-year period 3,065 patients with contact dermatitis were patch tested using a specific mix of fragrances. 509 (16.6%) patients were allergic to the

Cross-reactivity between citral and geraniol - can it be attributed to oxidized geraniol?

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BACKGROUND The fragrance compound geraniol is susceptible to autoxidation when in contact with air, and to cutaneous metabolism. In both processes, the isomeric aldehydes geranial and neral are formed. Citral consists of geranial and neral. Among patients with positive reactions to citral, we have

Aqueous 2% geraniol as a mosquito repellent failed against Aedes aegypti on ponies.

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Organic insect repellents are of interest to many agricultural producers and animal owners. Geraniol, a plant-derived alcohol, is naturally produced by a wide range of plants and is a US Environmental Protection Agency minimum risk pesticide. Previous studies have shown various concentrations of

Health impact assessment of a skin sensitizer: Analysis of potential policy measures aimed at reducing geraniol concentrations in personal care products and household cleaning products.

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A methodology to assess the health impact of skin sensitizers is introduced, which consists of the comparison of the probabilistic aggregated exposure with a probabilistic (individual) human sensitization or elicitation induction dose. The health impact of potential policy measures aimed at reducing

Allergic and photoallergic contact dermatitis from ketoprofen: evaluation of cross-reactivities by a combination of photopatch testing and computerized conformational analysis.

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Allergic contact dermatitis (ACD) and photo-ACD are cell-mediated delayed hypersensitivity reactions of the skin caused by a wide range of substances. Topical ketoprofen (KP), a nonsteroidal anti-inflammatory drug (NSAID), can induce ACD and photo-ACD. Patients with ACD and/or photo-ACD to KP

Overexpression of geraniol synthase induces heat stress susceptibility in Nicotiana tabacum.

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UNASSIGNED Transgenic tobacco plants overexpressing the monoterpene alcohol geraniol synthase exhibit hypersensitivity to thermal stress, possibly due to suppressed sugar metabolism and transcriptional regulation of genes involved in thermal stress tolerance. Monoterpene alcohols function in plant

Fragrance contact allergy: a 4-year retrospective study.

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BACKGROUND Fragrance chemicals are the second most frequent cause of contact allergy. The mandatory labelling of 26 fragrance chemicals when present in cosmetics has facilitated management of patients allergic to fragrances. OBJECTIVE The study was aimed to define the characteristics of the

Geraniol suppresses proinflammatory mediators in phorbol 12-myristate 13-acetate with A23187-induced HMC-1 cells.

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UNASSIGNED Geraniol is a monoterpene alcohol that has anti-fungal, anti-cancer and anti-nociceptive properties, but its anti-allergic rhinitis (AR) property is unclear. UNASSIGNED In this study, the anti-inflammatory role and its possible mechanisms of geraniol in human mast cell line (HMC-1) cells

[Comparison of chemical composition of selected essential oils used in respiratory diseases].

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BACKGROUND Essential oils are fragrances extracted from plants. They have a smooth consistency and pleasant smell. Essential oils have been applied in aromatherapy, cosmetics, food and pharmaceutical products. The aim of the study was to analyze the composition of selected essential oils used in

Characterization of T cell responses to fragrances.

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Fragrances are worldwide a major cause of allergic contact dermatitis (ACD), a delayed-type hypersensitivity reaction mediated by T lymphocytes. We investigated T cell responses to fragrances using peripheral blood mononuclear cells (PBMC) and T cells from skin lesions of fragrance-allergic

Allergenicity evaluation of fragrance mix and its ingredients by using ex vivo local lymph node assay-BrdU endpoints.

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The present studies were performed to compare the differences between sensitization potency of fragrance mix and its ingredients (oak moss absolute, isoeugenol, eugenol, cinnamal, hydroxycitronellal, geraniol, cinnamic alcohol, alpha amyl cinnamal), by using ex vivo LLNA-BrdU ELISA. The SI and EC3

Testing with fragrance mix. Is the addition of sorbitan sesquioleate to the constituents useful?

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In a multicentre study, the value of adding sorbitan sesquioleate (SSO) to the constituents of the 8% fragrance mix (FM) was investigated. In 7 centres, 709 consecutive patients were tested with 2 types of FM from different sources, its 8 constituents with 1% SSO, its 8 constituents without SSO, and

Content of fragrance mix ingredients and customer complaints of cosmetic products.

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BACKGROUND In relation to the wide use of cosmetics, serious adverse effects are rare. Occasionally, unwanted effects such as contact dermatitis are reported. Allergic reactions to cosmetics are often caused by fragrances. OBJECTIVE The aim was to investigate the content of fragrance mix (FM)

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