hypokalemia/triglyceride

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Factors associated with Hypokalemia in Continuous Ambulatory Peritoneal Dialysis Patients.

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Hypokalemia is a frequent problem in patients on continuous ambulatory peritoneal dialysis (CAPD) and is affected by multiple factors. To evaluate factors associated with hypokalemia, we studied 68 patients on maintenance CAPD treatment for at least six months. In univariate analysis, patients with

Effect of rapid weight loss with supplemented fasting on serum electrolytes, lipids, and blood pressure.

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The effect of rapid weight reduction with supplemented fasting was studied in a group of 46 individuals with moderate to severe obesity. The preparation used contained a mixture of protein, carbohydrate, and essential fatty acids providing 420 kcal daily. It was supplemented with a complement of

Rationale for calcium entry-blocking drugs in systemic hypertension complicated by coronary artery disease.

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There is considerable rationale for the use of the calcium entry-blocking drugs for the treatment of hypertension and prevention of recurrent episodes of angina pectoris in patients with systemic hypertension and significant coronary artery disease--the 2 entities commonly occurring together.

Low-dose bisoprolol/hydrochlorothiazide: an option in first-line, antihypertensive treatment.

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Two recent, multicenter, double-blind, placebo-controlled studies established the efficacy and safety of low-dose bisoprolol/hydrochlorothiazide (HCTZ) in patients with mild to moderate essential hypertension. Bisoprolol, a cardioselective beta-blocker, was used in a dose of 2.5 mg, 5 mg, or 10 mg.

Metabolic considerations in the choice of therapy for the patient with hypertension.

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The objective of treating patients with hypertension is not simply to reduce blood pressure but rather to prevent the associated morbidity and mortality. Recent assessments of clinical trials have shown that while the risk of stroke is consistently lower with antihypertensive therapy, the same

Genetics of pleiotropic effects of dexamethasone.

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Glucocorticoids such as dexamethasone have pleiotropic effects, including desired antileukemic, anti-inflammatory, or immunosuppressive effects, and undesired metabolic or toxic effects. The most serious adverse effects of dexamethasone among patients with acute lymphoblastic leukemia are

Long-term improvement in renal function with sirolimus after early cyclosporine withdrawal in renal transplant recipients: 2-year results of the Rapamune Maintenance Regimen Study.

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BACKGROUND The purpose of this study was to evaluate early cyclosporine (CsA) withdrawal from a sirolimus (SRL)-CsA-steroid (ST) regimen. METHODS Within 48 hr after transplantation, 525 primary (90%) or secondary (10%) renal allograft recipients with cadaveric (89%) or living (11%) donors received 2

Change of Cyclosporine Absorption over the Time after Kidney Transplantation.

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BACKGROUND Although the immunosuppressant cyclosporine (CsA) is widely used after kidney transplantation over the long term, there is still no firm consensus on the best way to monitor of CsA blood levels. OBJECTIVE Cyclosporine (CsA) assay is critical for the management of renal transplant

Metabolic side effects of diuretics and beta-adrenoceptorblockers.

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A review is made of the metabolic side effects of diuretics and beta-adrenoceptorblockers. The review is based on results from a population study, performed by the author, of women and on a survey of the literature. While diuretics give rise to hypokalemia, which may be of clinical importance,

New perspectives in the treatment of hypertension with arterial disease.

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The results of large-scale clinical trials of the therapy of mild hypertension have cast some doubts upon the routine use of current approaches in those at relatively low risk. Therefore, we must consider both the relative degree of risk for the individual patient and the potential risks of the

Indapamide. Effects on apoprotein, lipoprotein, and glucoregulation in ambulatory diabetic patients.

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We evaluated the long-term effects of indapamide, a non-thiazide diuretic, on blood pressure, glucoregulation, free insulin and C-peptide levels, and lipoprotein and apoprotein metabolism in 13 hypertensive diabetic patients for 24 weeks. Indapamide significantly reduced both systolic and diastolic

Thiazide-induced disturbances in carbohydrate, lipid, and potassium metabolism.

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Long-term thiazide diuretic therapy for hypertension is associated with disturbances in carbohydrate, lipid, and potassium metabolism that theoretically may have serious adverse effects. It appears that diuretic-induced hypokalemia interferes with production of insulin, producing mild elevations of

A double-blind comparison of perindopril and hydrochlorothiazide-amiloride in mild to moderate essential hypertension.

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The aim of this 3-month double-blind multicenter trial was to compare the antihypertensive efficacy and tolerability of the ACE inhibitor perindopril with those of a diuretic combination. After 1 month of receiving placebo, 165 patients with essential hypertension were randomised to perindopril 4 mg

How often do we face side effects of sirolimus in pediatric renal transplantation?

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We analyzed 25 pediatric renal transplantation patients on sirolimus (SRL) therapy to assess changes in serum creatinine, glomerular filtration rate, electrolytes, triglycerides, cholesterol, and side effects. Mean time to initiate SRL therapy was 3.2 years. The serum creatinine levels of patients

Long-term effectiveness of indapamide in hypertension: neural, renin and metabolic responses.

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Indapamide conferred effective blood pressure control over the six-month period of study. Blood sugar was elevated slightly in some patients. Hypokalemia occurred commonly within four to six weeks of initiating therapy and was corrected with oral potassium supplementation. There were no changes in

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