HIV positive patients on nevirapine containing regimen, taking Moringa oleifera leaf powder

HIV positive patients on efavirenz containing regimen, taking Moringa oleifera

HIV positive patients on nevirapine containing regimen, taking Moringa oleifera leaf powder
Moringa oleifera: leaf powder, 1.85g once daily as hard gelatin capsules

Nevirapine

HIV positive patients on efavirenz containing regimen, taking Moringa oleifera
Moringa oleifera: leaf powder, 1.85g once daily as hard gelatin capsules

Efavirenz

Total

Sex: Female, Male

Weight

Area under the plasma concentration time curve, determined using a non-compartmental approach by means of the Phoenix WinNonlin software application. Time points for sample collection were 0.5, 1, 1.5, 2, 3, 4, 6, 8 and 12 h

HIV positive patients on nevirapine containing regimen, taking Moringa oleifera leaf powder
Moringa oleifera: leaf powder

HIV positive patients on efavirenz containing regimen, taking Moringa oleifera
Moringa oleifera: leaf powder

plasma concentration 12h post dose, determined using a non-compartmental approach by means of the Phoenix WinNonlin software application. Time points for sample collection were 0.5, 1, 1.5, 2, 3, 4, 6, 8 and 12 h

C12h

Maximum plasma concentration post does, determined using a non-compartmental approach by means of the Phoenix WinNonlin software application. Time points for sample collection were 0.5, 1, 1.5, 2, 3, 4, 6, 8 and 12 h

Cmax

HIV positive patients on efavirenz containing regimen, taking Moringa oleifera leaf powder

Washout Day 0

Baseline Day 22

Day 35

Tsitsi G Monera-Penduka

leaf powder, 1.85g once daily, hard gelatin capsules

hypoxis hemerocallidea/antioksidan

Moringa Oleifera- Antiretroviral Pharmacokinetic Drug Interaction

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