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This application is a U.S. national stage of PCT/EP2017/066002 filed on 28 Jun. 2017, which claims priority to and the benefit of Italian Application No. 102016000067621 filed on 29 Jun. 2016, the contents of which are incorporated herein by reference in their entireties.
TECHNICAL FIELD OF
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BACKGROUND OF THE INVENTION
Cyclosporine is a metabolite isolated from the culture broths of the fungal species Tolypocladium inflatum Gams. A neutral, hydrophobic cyclic peptide composed of eleven amino acid residues, cyclosporine includes a previously unknown N-methylated amino acid composed of
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