Ibuprofen 800mg IV piggyback and Saline IVP q 6 hours x 4 during uterine fibroid embolization

Acetaminophen 1 gram IV piggyback and Saline IVP q6 hours x 4 during uterine fibroid embolization

Ibuprofen 800 mg/ Acetaminophen 1 gram IV piggyback and Saline IVP 6 hours x 4 during uterine fibroid embolization

Saline/Saline IV piggyback and IVP Ketorolac 30 mg q6 hours x 4 during uterine fibroid embolization

Ibuprofen 800mg IV piggyback and Saline IVP q 6 hours x 4.
IV Ibuprofen

Intravenous Ibuprofen

Acetaminophen 1 gram IV piggyback and Saline IVP q6 hours x 4
IV Acetaminophen

Intravenous Acetaminophen

Ibuprofen 800 mg/ Acetaminophen 1 gram IV piggyback and Saline IVP 6 hours x 4
IV Ibuprofen
IV Acetaminophen

IV Ibuprofen/IV Acetaminophen

Saline/Saline IV piggyback and IVP Ketorolac 30 mg q6 hours x 4
IV Placebo

Intravenous Placebo/Intravenous Placebo

Total

Sex: Female, Male

Region of Enrollment

Primary efficacy objective is to compare the change in maximum level of pain experienced by patient over 24 hours between IV acetaminophen and IV ibuprofen (alone and in combination), and the current standard of care medication regimen. This comparison will be measured using a visual analog scale (VAS) from 0 to 10, 0 signifying no pain and 10 signifying the worst possible pain. The scores reported are the mean of all patients' VAS scores in each respective category.

Evaluation of Maximum Pain Intensity Change Over 24 Hours With the Addition of IV Acetaminophen and IV Ibuprofen

Primary efficacy objective is to compare the change in mean pain intensity score over 24 hours between IV acetaminophen and IV ibuprofen (alone and in combination), and the current standard of care medication regimen. This comparison will be measured using a visual analog scale (VAS) from 0 to 10, 0 signifying no pain and 10 signifying the worst possible pain. The scores reported are the mean of all patients' VAS scores in each respective category.

Evaluation of Mean Pain Intensity Over 24 Hours With the Addition of IV Acetaminophen and IV Ibuprofen

Assessment of mean nausea by mean of VAS scores over a 24-hour period. VAS score is measured using a scale of 0 to 10, 0 signifying no nausea and 10 signifying the worst possible nausea. The scores reported are the mean of all patients' VAS scores in each respective category.

Mean Nausea Intensity

Mean opioid consumption in morphine equivalents over 24 hours

Opioid Consumption

Mean dose of anti-emetic medication in milligrams given over 24 hours

Anti-Emetic Consumption

Assessment of maximum level of nausea experienced by patient, by mean of VAS scores over a 24-hour period. VAS score is measured using a scale of 0 to 10, 0 signifying no nausea and 10 signifying the worst possible nausea. The scores reported are the mean of all patients' VAS scores in each respective category.

Maximum Nausea Intensity

Overall Study

Director of Clinical Research

Symptomatic Uterine Fibroids and Adenomyosis

IV Ibuprofen

IV Acetaminophen

Intravenous placebo/Intravenous placebo

Ronald Reagan UCLA Medical Center

Santa Monica/UCLA Medical Center and Orthopaedic Hospital

Effectiveness of IV Acetaminophen and IV Ibuprofen in Reducing Post Procedural Pain in the UFE Procedure

A Prospective, Double Blind, Randomized, Placebo Controlled Study to Compare the Effectiveness of Intravenous Acetaminophen and Intravenous Ibuprofen in Reducing Post Procedural Pain in the Uterine Fibroid Embolization Procedure

Cheryl Hoffman

University of California, Los Angeles

Sponsor Name Pending

patients in this group were submitted to extracorporeal shockwave lithotripsy (SWL) 3000 impulses at 60 impulses per minute under general anesthesia. Unique session

patients in this group were submitted extracorporeal shockwave lithotripsy (swl) to 4000 impulses at 90 impulses per minute under general anesthesia- unique session

Urinary (Renal or Ureteral) Stones

patients were submitted to one session SWL at a Dornier Compact Delta lithotripter under general anesthesia under supervision of an anesthesiologist and an urologist.

extracorporeal shockwave lithotripsy (SWL)

University of Sao Paulo General Hospital

Comparison Between Two Shock Wave Regimens for Treating Urinary Stones

Comparison Between Two Shock Wave Regimens Using Frequencies of 60 and 90 Impulses Per Minute for Urinary Stones

patients submitted to SWL in two different regimens were submited to renal ultrasound and abdominal x rays (KUB) three months after procedure to check the occourrence of stone-free status, residual fragments or unmodified stone.

patients submitted to two different SWL regimens were followed clinically and submited to renal ultrasound and abdominal x ray to check the occurrence of adverse effects like hematoma or peri renal collections.

EDUARDO MAZZUCCHI

Ulcerative Colitis

conventional white light colonoscopy

FICE (Fujinon Intelligent Chromoendoscopy)

Departement d'Endoscopie digestive - Hopital Archet 2, CHU de Nice

Comparison Between Chromoendoscopy and Conventional Colonoscopy to Improve the Detection of Neoplasia in Patients With Ulcerative Colitis (UC)

Comparaison de la Chromo Endoscopie Virtuelle FICE (Fujinon Intelligent Chromoendoscopy) Avec la Coloscopie Conventionnelle Dans la détection de la Dysplasie Chez Patients Porteurs de Recto Colite ulcéro hémorragique (RCH).

inflammation/scopolamine

Effectiveness of IV Acetaminophen and IV Ibuprofen in Reducing Post Procedural Pain in the UFE Procedure

Comparison Between Two Shock Wave Regimens for Treating Urinary Stones

Comparison Between Chromoendoscopy and Conventional Colonoscopy to Improve the Detection of Neoplasia in Patients With Ulcerative Colitis (UC)

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