linoleic acid/obesity

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[Effects of conjugated linoleic acid on obese MSG mice with insulin resistance].

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OBJECTIVE To study the effect of conjugated linoleic acid (CLA) on obese MSG mice with insulin resistance. METHODS About four months old, obese MSG mice with insulin resistance were divided into control, CLA and rosiglitazone groups and drugs were administrated ig once a day. Body weights were

[The conjugated linoleic acids in prevention and treatment of obesity].

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The results of up-to-date performed experimental studies indicated that conjugated linoleic acids (CLA) contained in diet lead to significant both adipose tissue and body mass decrease. It suggests that the CLA-rich diet or CLA-contained medicines can be useful in prevention and treatment of obesity

Are conjugated linolenic acid isomers an alternative to conjugated linoleic acid isomers in obesity prevention?

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Despite its benefits, conjugated linoleic acid (CLA) may cause side effects after long-term administration. Because of this and the controversial efficacy of CLA in humans, alternative biomolecules that may be used as functional ingredients have been studied in recent years. Thus, conjugated

Conjugated linoleic acid improves airway hyper-reactivity in overweight mild asthmatics.

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BACKGROUND Conjugated linoleic acids (CLA) are naturally occurring fatty acids that have multiple biological properties including the regulation of metabolic, proliferative and immune processes. OBJECTIVE The aim of this study was to investigate the efficacy and safety of CLA as a dietary supplement

[Gene expression of resistin and the effect of conjugated linoleic acid on its expression of obese rat fed with high fat diet].

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OBJECTIVE To study the gene expression of the resistin and the effects of conjugated linoleic acid on its expression in white adipose tissue of obese rats fed with high fat diet during the formation of insulin resistance. METHODS Male Wistar rats were randomly separated in control group, high-fat

Safety profile of conjugated linoleic acid in a 12-month trial in obese humans.

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Conjugated linoleic acid (CLA) is marketed in numerous commercially available dietary supplements, but few studies have looked at the long-term safety of this product. The current study evaluated the safety of one CLA product (Clarinol) over a one-year period in obese humans who were generally

[Effect of conjugated linoleic acid on gene expression of adiponectin of obese rat fed with high fat diet].

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OBJECTIVE To study the effect of conjugated linoleic acid (CLA) on expression of adiponectin in white adipose tissue of obese rats. METHODS Male Wistar rats were randomly divided into control group, high-fat group and high fat + CLA group (0.75 g, 1.50 g, 3.00 g per hundred gram diet weight), we

The rs1527483, but not rs3212018, CD36 polymorphism associates with linoleic acid detection and obesity in Czech young adults.

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Recent evidence has raised the possibility of the existence of a sixth taste modality - that is, taste for fat - which is mediated by lingual CD36 and plays a role in obesity. Consequently, the genetic polymorphism of CD36 has been shown to be associated with altered oro-sensory detection of dietary

Effect of conjugated linoleic acid on body fat accretion in overweight or obese children.

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BACKGROUND Conjugated linoleic acid (CLA) is a supplemental dietary fatty acid that decreases fat mass accretion in young animals. OBJECTIVE The aim of this study was to determine CLA's efficacy with regard to change in fat and body mass index (BMI; in kg/m(2)) in children. METHODS We conducted a 7

Dietary conjugated linoleic acid preserves pancreatic function and reduces inflammatory markers in obese, insulin-resistant rats.

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Pancreatic preservation is an important part of diabetes management that may occur with improved peripheral insulin sensitivity and attenuated low-grade adipose tissue inflammation. The objective of the current study was to determine the response of obese, insulin-resistant fa/fa Zucker rats vs lean

Supplementation with trans10cis12-conjugated linoleic acid induces hyperproinsulinaemia in obese men: close association with impaired insulin sensitivity.

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OBJECTIVE Hyperproinsulinaemia reflects both beta cell dysfunction and insulin resistance in cross-sectional studies, but it is not known whether changes in proinsulin concentrations are related to insulin resistance over time. As trans10cis12 (t10c12)-conjugated linoleic acid (CLA) supplementation

The Effect of Conjugated Linoleic Acid Supplementation on Body Composition, Serum Insulin and Leptin in Obese Adults.

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Studies have reported contradictory findings regarding the effect of a mixture of 2 conjugated linoleic acid (CLA) isomers on body weight and some serum indices. This study aims to investigate the effect of daily supplementation of these 2 isomers on body composition and serum leptin

Contrasting apoptotic responses of conjugated linoleic acid in the liver of obese Zucker rats fed palm oil or ovine fat.

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We hypothesized that reducing weight properties of conjugated linoleic acid (CLA) are due to adipocyte apoptosis and that CLA differentially modulates the apoptotic responses in hepatic lipotoxicity from rats fed saturated fat diets. Obese Zucker rats were fed atherogenic diets (2%w/w of

Dietary conjugated linoleic acid does not adversely affect bone mass in obese fa/fa or lean Zucker rats.

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Conjugated linoleic acid (CLA) elevates body ash in healthy animals. The objective of the present study was to determine if single or mixed CLA isomers improve bone mass in an obese and hyperinsulinemic state. Male (n = 120) lean and obese fa/fa Zucker rats (age, 6 weeks) were randomized to 8 weeks

[Influence of dietotherapy enriched with conjugated linoleic acid on anthropometrical indicators and body composite structure in patients with an overweight].

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The clinical efficiency of dietotherapy enriched with conjugated linoleic acid (3 g per day) in patients, suffering from the excess mass of a body and obesity of I and II degrees has been investigated. Dynamics of anthropometrical indicators and body composite structure before and after the

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