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lolium perenne/ataxia
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Brain damage by extracts of parasitised annual ryegrass (Lolium rigidum) in nursling rats.
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Extracts of annual ryegrass (Lolium rigidum) infected with Anguina sp. and Corynebacterium sp., and associated with an outbreak of annual ryegrass toxicity in sheep, were administered to 2-week-old rats by a single intraperitoneal injection. Rats that received a lethal dose of toxin developed
Staggers induced by consumption of perennial ryegrass in cattle and sheep from northern California.
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Staggers was diagnosed in sheep and cattle from the northern California coast. The diagnosis was made on the basis of history of ingestion of perennial ryegrass (Lolium perenne) stubble, clinical signs of transient ataxia, which was aggravated by stimulation, and nearly complete recovery after
Ryegrass staggers in heifers: a new mycotoxicosis in Argentina.
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Aberdeen Angus (AA) and crossbred AA x Hereford 8-9 mo old heifers (560 animals) showed a typical perennial ryegrass (PRG) staggers syndrome after grazing 26 d in a 25-hectare paddock of pure Lolium perenne. Effects were observed in about 50% of the herd. When forced to move, the animals showed
A single exposure to the tremorgenic mycotoxin lolitrem B inhibits voluntary motor activity and spatial orientation but not spatial learning or memory in mice.
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The indole diterpenoid toxin lolitrem B is a tremorgenic agent found in the common grass species, perennial ryegrass (Lolium perenne). The toxin is produced by a symbiotic fungus Epichloë festucae (var. lolii) and ingestion of infested grass with sufficient toxin levels causes a movement disorder in
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