malaria/edema

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Convalescent Plasma Treatment in COVID-19

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Objective: To investigate the efficacy and safety of transfusing convalescent plasma collected from patients who have recovered from COVID-19 disease to patients admitted at Aga Khan University Hospital for the management of active COVID-19 disease. Methods: A. Study design Non-randomized open Label

TES Artemether-lumefantrine for Pf and Chloroquine (CQ) for Pv

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1. BACKGROUND In 2002, the Philippines changed its antimalarial drug policy to the combination treatment, CQ+ Sulphadoxine-pyrimethamine (SP) as 1st-line treatment and artemether-lumefantrine as 2nd-line treatment. The Department of Health (DOH) prescribed the use of artemether-lumefantrine (AL)

Monitoring of Perfusion in Sepsis and Malaria

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This will be a single center, prospective, longitudinal, observational study of patients with sepsis or severe malaria. It is planned that this initial observational study will inform a follow-up intervention study, based on the observational study findings (Lung Ultrasound and Passive Leg Raising-

Biomedical Investigations for Optimized Diagnosis and Monitoring of Severe Acute Malnutrition (SAM): Elucidating the Heterogeneous Diagnosis of SAM by Current Anthropometric Criteria and Moving Beyond

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DIAGNOSTIC DISCREPANCY According to WHO experts, WHZ and MUAC can be used independently to indicate severe acute malnutrition (WH. There is however a significant and sometimes huge discrepancy between these two criteria: they do not usually identify the same children as acutely malnourished;

Optimal Fluid Management in Adult Severe Malaria

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Background Fluid therapy in severe malaria and severe sepsis. Severe falciparum malaria causes multiple organ dysfunction including metabolic acidosis, coma, anemia, acute kidney injury (AKI), and pulmonary edema. The mortality rate of the disease is still around 15-23% despite optimal antimalarial

Evaluation of Reproducibility of a Sporozoite Challenge Model for Plasmodium Vivax in Human Volunteers

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Study design A randomized, open-label clinical trial was designed to standardize a P. vivax sporozoite challenge model in malaria-naïve volunteers, specifically, the relationship between the number of infectious mosquito bites and the likelihood of developing patent parasitemia detectable by

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Herbal & Natural Medicine

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