malaria/triglyceride

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The effect of plasma free fatty acids and long-chain triglycerides on glucose metabolism in uncomplicated falciparum malaria.

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To investigate the therapeutic potential of increased plasma free fatty acid (FFA) and triglyceride concentrations in hypoglycaemic patients receiving quinine, 32 untreated Thai adults with uncomplicated falciparum malaria were allocated at random to one of 4 regimens: 2 mg/kg/min dextrose infused

Epistatic Interactions between apolipoprotein E and hemoglobin S Genes in regulation of malaria parasitemia.

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Apolipoprotein E is a monomeric protein secreted by the liver and responsible for the transport of plasma cholesterol and triglycerides. The APOE gene encodes 3 isoforms Ɛ4, Ɛ3 and Ɛ2 with APOE Ɛ4 associated with higher plasma cholesterol levels and increased pathogenesis in several infectious

Serum Lipids and Lipoproteins During Uncomplicated Malaria: A Cohort Study in Lambaréné, Gabon.

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AbstractThe serum lipid profile in malaria patients has been found to differ from that of healthy controls. We investigated serum lipid profile changes in malaria patients over time compared with patients with other febrile diseases. In total, 217 patients were included in the study (111 malaria

Placental malaria and modulation of immune and hormonal responses in Cameroonian women.

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Adverse pregnancy outcomes place the lives of mother and new born babies in jeopardy, especially in Sub Saharan Africa. Although a well-balanced network of the pregnancy-associated hormones and lipid fractions is necessary for healthy pregnancy, the profiles of some of these biomarkers alongside

Variation in common lipid parameters in malaria infected patients.

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The heart is remarkably resilient even in the face of heavy parasite sequestration and other vital organ dysfunction, and deaths from cardiac arrhythmias in severe malaria are rare. Malaria may prove fatal for patients with pre-existing cardiac failure due to valvular stenosis or myocardial disease.

The impact of malaria on common lipid parameters.

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No data are available in the literature to indicate whether low-level Plasmodium falciparum infections induce lipid parameter changes. We hypothesized that low-level P. falciparum infections induce significant changes in common lipid parameters. We retrospectively selected samples from a malaria

Efficient weapon for protracted warfare to malaria: A chondroitin sulfate derivates-containing injectable, ultra-long-lasting meshy-gel system.

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Progress at elimination of malaria is limited by the challenges of reaching large rural population and ensuring patient adherence to adequate pharmacologic treatment. In the present study, a novel material (octadecylamine modified chondroitin sulfate) was synthesized, to fabricate a long acting

Hypertriglyceridemia as an indicator of the severity of falciparum malaria in returned travelers: a clinical retrospective study.

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To test the hypothesis that the magnitude of plasma triglyceride changes could be related to the severity of falciparum malaria, we performed a retrospective case-control study from January 1999 to December 2000 among hospitalized patients with fever who were returning to France from the tropics.

Altered plasma lipid pattern in falciparum malaria.

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Plasma levels of HDL, LDL, total cholesterol and triglycerides were measured in 60 patients with falciparum malaria (37 severe cases and 23 mild) and in 83 healthy individuals, to study malaria-induced changes in plasma lipids. Triglyceride levels were lower in the patients than in the controls but

Changes in serum lipid profile in the acute and convalescent Plasmodium vivax malaria: A cohort study.

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Although serum lipids are known to be altered in Plasmodium falciparum-induced malaria, little is known about such changes due to Plasmodium vivax infection. This cohort study assessed serum concentrations of triglycerides, total cholesterol, low-density lipoprotein (LDL), and high-density

Blood lipid changes in repeated infections of vivax malaria.

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Alterations in the levels of plasma and erythrocyte membrane lipids in fresh and repeated P. vivax malarial patients were studied. A significant fall in plasma cholesterol and phospholipids was observed in repeated malaria. The decrease was highly significant when the number of attacks were more

Association of lipid levels with mefloquine and carboxy-mefloquine concentrations in patients with uncomplicated falciparum malaria.

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Mefloquine shows a high capacity to bind plasma proteins, which influences the amount of drug in erythrocytes. The study investigated the association of lipids levels with plasma concentrations of mefloquine and carboxy-mefloquine in 85 Brazilian patients with uncomplicated falciparum malaria. There

Lipid Profile of Children with Malaria by Plasmodium vivax.

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Background. Changes in lipid profile are commonly reported in adult patients with malaria. However, a few studies evaluated lipid abnormalities in children continuously exposed to P. vivax. Objective. To evaluate lipid abnormalities in children with P. vivax infection and to assess if parasite count

[Changes of serum lipoproteins during the course of human malaria (author's transl)].

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Triacylglycerides (TAG), total cholesterol (TC) and serum lipoproteins (SLP) were studied during the course of 12 cases of human malaria and one case of simian inui malaria. The erythrocytic schizogony induced quickly an increase of TAG, a decrease of TC and modifications of SLP such an increase of

[HDL cholesterol as a sensitive diagnostic parameter in malaria].

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In patients with malaria the lipid parameters triglycerides, cholesterol, and HDL-cholesterol were determined routinely. At the time of admission hypertriglyceridemia, hypocholesterolemia, and an extreme decrease in HDL-cholesterol were found. This dyslipoproteinemia was present in cases of

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