mannan/edema

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Inhibition of lectin-mediated innate host defences in vivo modulates disease severity during influenza virus infection.

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Host-mediated recognition of mannose-rich glycans on the surface of pathogens represents an ancient mechanism of innate immune defence. In this study, we demonstrate that the virus strains that differ in the degree of N-linked glycosylation on the globular head of their hemagglutinin glycoprotein

Membrane proteome analysis of cerulein-stimulated pancreatic acinar cells: implication for early event of acute pancreatitis.

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OBJECTIVE Cerulein pancreatitis is similar to human edematous pancreatitis with dysregulation of the production and secretion of digestive enzymes, edema formation, cytoplasmic vacuolization and the death of acinar cells. We hypothesized that membrane proteins may be altered as the early event

[Studies on brewer's yeast (II). Phlogistic action (author's transl)].

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Yeast has a phlogistic effect, and the inflammatory action of 10 brewer's yeast samples fractionated by autolysis and/or destruction of the cell wall was studied in rat hind paw. The yeast samples produced a dose dependent edema when given subcutaneously into the paw. The samples obtained by

Polysaccharides in fungi. XIV. Anti-inflammatory effect of the polysaccharides from the fruit bodies of several fungi.

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Anti-inflammatory assays on the carrageenin-induced edema and scald-induced hyperalgesia in the hindpaw of rats were studied on polysaccharides obtained from the fruit bodies of various fungi (polysaccharide AC, BC: Tremella fuciformis;MEA, MHA, MCW-A, MCW-N: Auricularia auricula-judae; T-2-HN:

Involvement of mannose receptor in the preventive effects of mannose in lipopolysaccharide-induced acute lung injury.

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Although macrophage mannose receptor contributes to the anti-inflammatory procedure, its mechanisms of action are incompletely understood in acute lung injury. We recently found that mannose which could bind to mannose receptor, prevented acute lung injury in rats. Here, we profiled the involvement

MASP-1 Increases Endothelial Permeability.

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Pathologically increased vascular permeability is an important dysfunction in the pathomechanism of life-threatening conditions, such as sepsis, ischemia/reperfusion, or hereditary angioedema (HAE), diseases accompanied by uncontrolled activation of the complement system. HAE for example is caused

Structure determination of polysaccharides in Aloe saponaria (Hill.) Haw. (Liliaceae).

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Neutral polysaccharides that inhibit carrageenin-induced edema in rats were isolated from the nondialysate of the pulp of Aloe saponaria by gel filtration. These were shown to be a linear polymer of a 1,4-linked beta-D-mannopyranose (mol. wt. 15,000) containing 18% acetyl groups (As mannan 1), and a

Decreased mortality of Norman murine sarcoma in mice treated with the immunomodulator, Acemannan.

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An extract from the parenchyma of Aloe barbadensis Miller shown to contain long chain polydispersed beta (1,4)-linked mannan polymers with random O-acetyl groups (acemannan, Carrisyn) was found to initiate the phagocyte production of monokines that supported antibody dependent cellular cytotoxicity

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