menorrhagia/headache

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Headache as a Consequence of Menorrhagia and Utero-Ovarian Irritation.

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Long-term treatment of menorrhagia with mefenamic acid.

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Thirty-six women with menorrhagia were treated with mefenamic acid during all menstrual periods for more than 1 year. These women had experienced objective and subjective benefit--menstrual blood loss was reduced and other menstrual symptoms improved during a preliminary 4-cycle double-blind

Safety of tranexamic acid in women with heavy menstrual bleeding: an open-label extension study.

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OBJECTIVE An open-label, extension clinical study was conducted to assess the safety of a novel, oral formulation of tranexamic acid (TA) in women with cyclic heavy menstrual bleeding. METHODS Eligible patients who completed either a three- or six-cycle double-blinded clinical trial of TA were

Oral modified-release tranexamic acid for heavy menstrual bleeding.

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OBJECTIVE To review the pharmacology, pharmacokinetics, efficacy, and safety profile of an oral modified-release (MR) formulation of tranexamic acid. METHODS Literature was accessed through MEDLINE (1966-July 2012), Iowa Drug Information Service (1997-July 2012), and bibliographies of pertinent

Oral contraceptives and DDAVP nasal spray: patterns of use in managing vWD-associated menorrhagia: a single-institution study.

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The purpose of this study was to examine patterns of use for oral contraceptive and desmopressin acetate nasal spray, both used in managing menorrhagia in adolescents with von Willebrand disease (vWD). Hospital records of adolescents with documented vWD and menorrhagia were reviewed retrospectively.

Treatment of menorrhagia with the levonorgestrel intrauterine system versus endometrial resection.

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OBJECTIVE Treatment of menorrhagia with levonorgestrel intrauterine system (LNG IUS) and transcervical resection. METHODS An open, therapeutic, randomized study. METHODS Central county hospital specializing in hysteroscopy. METHODS Two parallel groups of 30 subjects each. METHODS Thirty patients had

Efficacy and safety of ormeloxifene in management of menorrhagia: a pilot study.

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OBJECTIVE To assess the efficacy and safety of ormeloxifene (centchroman) in the medical management of menorrhagia. METHODS Forty-two women with menorrhagia were recruited for the study. Ormeloxifene was given to each patient 60 mg twice a week for 3 months and then once a week for 1 month. Patients

Treatment of menorrhagia with meclofenamate sodium.

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A double-blind, placebo-controlled crossover trial was undertaken to determine the efficacy of meclofenamate sodium in the treatment of menorrhagia. Twenty-nine patients who had a baseline menstrual blood loss greater than 60 ml received 2 months' each of meclofenamate sodium, 100 mg by mouth, three

Long-term evaluation of safety and health-related quality of life in women with heavy menstrual bleeding treated with oral tranexamic acid.

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OBJECTIVE A multicenter, long-term, open-label study was conducted to assess the safety and health-related quality of life (HRQoL) of an oral tranexamic acid (TA) formulation in women with cyclic heavy menstrual bleeding (HMB). METHODS Following a screening menstrual cycle, women with a history of

Migraine is associated with menorrhagia and endometriosis.

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OBJECTIVE To evaluate the frequency of menorrhagia and endometriosis in female migraineurs compared to age-matched women without headache. BACKGROUND Migraine predominantly affects women of childbearing age and is often associated with the menstrual period, yet there is a paucity of data regarding

Elagolix Treatment for Up to 12 Months in Women With Heavy Menstrual Bleeding and Uterine Leiomyomas

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Objective: To investigate the safety and efficacy of elagolix, an oral gonadotropin-releasing hormone antagonist, with hormonal add-back therapy for up to 12 months in women with heavy menstrual bleeding associated with uterine leiomyomas.

Pre-operative endometrial thinning agents before endometrial destruction for heavy menstrual bleeding.

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BACKGROUND Heavy menstrual bleeding is one of the most common reasons for referral of premenopausal women to a gynaecologist. Although medical therapy is generally first line, many women eventually will require further treatment. Endometrial ablation by hysteroscopic and more recent

Severe Menorrhagia.

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A 15-year-old African-American female presented with prolonged menstrual bleeding accompanied by a 1-week history of weakness, fatigue, dizziness, and bifrontal headaches. Her previous period was 5 weeks earlier, lasted 3 weeks, with heavy passage of clots. Family history is significant for bleeding

[Severe thrombocytosis and leukocytosis associated with iron deficiency anaemia: a case-report].

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Reactive thrombocytosis (secondary thrombocytosis) is frequent and typically moderate. We report a case of extreme thrombocytosis and leukocytosis secondary to an iron deficiency anemia. A 21-year-old woman is admitted in emergency department for acute headache. Biological assessment reveals a

Transfusion-Related Acute Brain Injury: A Case Report on Reversible Cerebral Vasoconstriction Syndrome

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Reversible cerebral vasoconstriction syndrome (RCVS) manifests with a thunderclap headache and reversible vascular abnormalities. Red blood cell transfusions have not been well identified as a risk factor for RCVS. We report a rare case of acute brain injury resulting from RCVS after a packed red

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