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monosaccharide/dental caries

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Relative importance of polysaccharides, disaccharides and monosaccharides in the production of caries.

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Aromatic Hybrid Foldamer with a Hydrophilic Helical Cavity Capable of Encapsulating Glucose.

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An indolocarbazole-naphthyridine hybrid oligomer capable of adopting a stable helical conformation was prepared, and its folding properties were thoroughly studied in the solid state and in solution. As a result of folding, a hydrophilic cavity was generated inside the helix wherein monosaccharides

Characterization of multicomponent monosaccharide solutions using an enzyme-based sensor array.

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We report the development of a sensor for rapidly and simultaneously measuring multiple sugars in aqueous samples. In this strategy, enzyme-based assays are localized within an array of individually addressable sites on a micromachined silicon chip. Microspheres derivatized with
Here, a simple micro free-flow electrophoresis (μFFE) was developed for fluorescence sensing of monosaccharide via supermolecule interaction of synthesized boronic acid functionalized benzyl viologen (ο-BBV) and fluorescent dye. The μFFE contained two open electrode cavities and an ion-exchange

Relative consumption of sucrose and other sugars: has it been a factor in reduced caries experience?

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This paper examines the impact on the development of caries, especially on the proximal and the free smooth surfaces, that follows the reduction in sucrose consumption and the increase in consumption of the monosaccharides in the United States and Great Britain. Laboratory evidence shows that

Frequency-agile terahertz-wave parametric oscillator in a ring-cavity configuration.

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We demonstrate a frequency-agile terahertz wave parametric oscillator (TPO) in a ring-cavity configuration (ring-TPO). The TPO consists of three mirrors and a MgO:LiNbO(3) crystal under noncollinear phase-matching conditions. A novel, fast frequency-tuning method was realized by controlling a mirror
The lectin from the mushroom Psathyrella velutina recognises specifically N-acetylglucosamine and N-acetylneuraminic acid containing glycans. The crystal structure of the 401 amino acid residue lectin shows that it adopts a very regular seven-bladed beta-propeller fold with the N-terminal region

The critical role of dimer formation in monosaccharides binding to human serum albumin.

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Human serum albumin (HSA) is the most abundant transport protein found in human blood. HSA is known to bind a wide range of drugs and monosaccharides, but where and how these molecules bind are largely unknown. Recently, a crystal structure of glycated HSA has been reported, and interestingly, in

Characterization of IL-2-dependent cytotoxic T-cell clones. III. Inhibition of killing activity by monosaccharides.

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The effects of monosaccharides on the cytotoxic activity of cytotoxic T lymphocytes (CTL) and three cloned long-term cytotoxic T-lymphocyte lines (CTLL) are compared. Uncultured CTL and clones CTLL-A2 and CTLL-A11 were derived from the peritoneal cavity of C57BL/6 mice immunized against the H-2Dd

Streptococcus downii sp. nov., isolated from the oral cavity of a teenager with Down syndrome

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A new α-haemolytic streptococcal strain has been isolated from the dental plaque of a teenager with Down syndrome. Genetic and taxonomic analyses place this Streptococcus within the oralis group. It is a Gram-stain-positive, non-motile, non-spore-forming spherical alpha-haemolytic coccus
A general procedure is described for addressing the computer simulation of protein-carbohydrate interactions. First, a molecular mechanical force field capable of performing conformational analysis of oligosaccharides has been derived by the addition of new parameters to the Tripos force field; it

Diet and Dental Caries: The Pivotal Role of Free Sugars Reemphasized.

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The importance of sugars as a cause of caries is underemphasized and not prominent in preventive strategies. This is despite overwhelming evidence of its unique role in causing a worldwide caries epidemic. Why this neglect? One reason is that researchers mistakenly consider caries to be a

[Adhesion of lactic acid bacteria to epithelium of different cavities of the human organism].

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During investigation of adhesive properties of lactic acid bacteria it was found out that 11 strains adhered to buccal intestinal and vaginal epithelium of human. The highest adhesive activity was detected in enterococci (adhesive index 7.75-14.26), lower one--in streptococci (6.40-9.16). In
The reaction of [CpZrCl3(thf)2] with methyl 4,6-O-benzylidene-beta-D-glucopyranoside (beta-MeBGH2, 1) in the presence of Et3N results in the formation of the zirconate complex [Et3NH] [(CpZrCl)2(mu-Cl) (mu-(beta-MeBG)]2] (2). X-ray structure analyses were performed from the ligand precursor
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