mycose/atrophy

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[Effect of polyene antibiotics on the development of alcoholic-dietary fatty degeneration of the liver in rats].

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The effect of the sodium salts of levorin, isolevorin, nystatin and amphotericin B prepared with the use of sodium desoxycholate and amphoglucamine on the development of fatty degeneration of the liver was studied in rats. Fatty degeneration of the liver was induced in the animals by the diet

[Testing the sensitivity of opportunistic agents of mycoses to antimycotic drugs in vitro].

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The authors tried to standardize the method of assessment of the minimal inhibitory concentration (MIC) of antimycotics for the evaluation of the sensitivity of opportunistic causal agents of mycoses. They paid attention to factors which cause deterioration of the reproducibility of tests and lead

[Liposome amphotericin in the treatment of deep mycoses in patients not severely immunosuppressed. An efficient alternative with low toxicity].

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Amphotericin is a powerful antifungal agent of high toxicity. Encapsulation in liposomes has led to new perspectives although clinical experience is still slight. Four patients, who were neither carriers of antibodies against the human immunodeficiency virus nor neutropenic, diagnosed of meningeal

The role of CT in the evaluation of patients with intracranial CNS infectious-inflammatory disorders.

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Infections of the CNS may be caused by diverse etiologies. These include bacteria, viruses, mycoses, protozoa, helminths. In these CNS infections there is a breakdown in the blood-brain barrier. The most common clinical forms of intracranial CNS infections include meningitis, cerebritis-abscess

[Glucocorticoid-induced cutaneous adverse events].

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Glucocorticoids are largely used in therapy for many diseases with a noteworthy efficacy. However, the use of glucocorticoids by a systemic or local way (topical or inhaled) is associated with numerous cutaneous side effects. Long duration of treatment and high dosage are associated with more severe

Multisystemic fusariosis with fulminant evolution

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This report presents the case of a 13-year-old female patient with history of acute myeloid leukemia, who, after a bone marrow transplant, began to vomit and experienced rapidly progressive deterioration of consciousness, in addition to disseminated erythematous-violaceous macules, and some blisters

Clinical efficacy and safety of oral terbinafine in fungal mycetoma.

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OBJECTIVE An open-label study was performed to assess the efficacy and safety of terbinafine in the treatment of eumycetoma. METHODS Single-center, open-label study, including 27 patients with signs and symptoms of eumycetoma which had developed within 5 years and was confirmed by mycological

[Invasive candidiasis in a lung retransplantation recipient].

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BACKGROUND Lung-graft loss is a potential problem for the majority of lung-transplant recipients. Retransplantation could be a treatment option, despite significant morbidity and mortality due to infectious complications. The epidemiology, clinical presentation and early treatment are still the

Persistent neutrophilic meningitis. Report of four cases and review of the literature.

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Persistent neutrophilic meningitis is a poorly described variant of chronic meningitis characterized by the persistence of neutrophils in the CSF over extended periods of time (greater than 1 wk) in association with ongoing signs of meningeal inflammation and negative CSF cultures for bacteria and

A survey of the pathology of marmosets (Callithrix jacchus) under experiment.

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A survey of the pathology of 567 laboratory-bred cotton-eared marmosets (Callithrix jacchus) is presented. There were few significant pathological changes in animals used in studies up to 6 months in duration, suggesting that the marmoset can be a useful non-human primate species for routine

Concepts and principles of photodynamic therapy as an alternative antifungal discovery platform.

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Opportunistic fungal pathogens may cause superficial or serious invasive infections, especially in immunocompromised and debilitated patients. Invasive mycoses represent an exponentially growing threat for human health due to a combination of slow diagnosis and the existence of relatively few

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