papillon-lefevre disease/proline

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Structure of FBP11 WW1-PL ligand complex reveals the mechanism of proline-rich ligand recognition by group II/III WW domains.

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FBP11/HYPA is a mammalian homologue of yeast splicing factor Prp40. The first WW domain of FBP11/HYPA (FBP11 WW1) is essential for preventing severe neurological diseases such as Huntington disease and Rett syndrome and strongly resembles the WW domain of FCA, the essential regulator for flowering

High-Throughput Screening of Free Proline Content in Rice Leaf under Cadmium Stress Using Hyperspectral Imaging with Chemometrics

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Tracking of free proline (FP)-an indicative substance of heavy metal stress in rice leaf-is conducive to improve plant phenotype detection, which has important guiding significance for precise management of rice production. Hyperspectral imaging was used for high-throughput screening FP in rice

Proline partially overcomes excess molybdenum toxicity in cabbage seedlings grown in vitro.

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In vitro grown cabbage (Brassica oleracea var. capitata) seedlings exposed to excess molybdenum (Mo) ions exhibited severely reduced plant growth at the cotyledonary stage. Adding 80 mM proline (Pro) to the Mo-treated medium could help 50% seedlings to overcome the toxicity and grow true leaves.

[Exogenous nitric oxide accelerates soluble sugar, proline and secondary metabolite synthesis in Ginkgo biloba under drought stress].

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The effects of exogenous nitric oxide donor sodium nitroprusside (SNP) on substance metabolism of Ginkgo biloba leaves under drought stress were studied. The results showed that 250 micromol/L SNP (Fig.2) treatment under 35% relative soil water content (RSWC) stress (Fig.1) raised remarkably soluble

Effect of proline on biochemical and molecular mechanisms in lettuce (Lactuca sativa L.) exposed to UV-B radiation.

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The purpose of the present study was to evaluate the role of proline (Pro) in relieving UV-B radiation-induced oxidative stress in lettuce. Lettuce seedlings were exposed to 3.3 W m-2 UV-B radiation for 12 h after pre-treatment sprayed with 20 mM Pro. The data for malondialdehyde (MDA), hydrogen

Investigation of ZnO nanoparticles on proline, anthocyanin contents and photosynthetic pigments and lipid peroxidation in the soybean.

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The interaction between nanoparticles and plants is inevitable. In this study, the effect of different concentrations of ZnO nanoparticles synthesised using olive extract on the soybean was studied. The soybean seeds were cultured in a Hoagland medium containing agar which was treated different

PAL inhibitor evokes different responses in two Hypericum species.

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Accumulation of secondary metabolites (general phenols, naphthodianthrones and phloroglucinol hyperforin) in Hypericum perforatum and Hypericum canariense after application of the inhibitor (2-aminoindane-2-phosphonic acid, AIP) of the pivotal enzyme of general phenylpropanoid pathway (phenylalanine

The spike plays important roles in the drought tolerance as compared to the flag leaf through the phenylpropanoid pathway in wheat.

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The spike photosynthesis plays a curial role in wheat photosynthesis under drought stress. However, the mechanism of drought tolerance in the spike is still unclear. Our study compared the gas exchange parameters, antioxidant system, and phenylpropanoid pathway between the wheat flag leaf and spike

Metabolomic studies on geographical grapes and their wines using 1H NMR analysis coupled with multivariate statistics.

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Environmental vineyard conditions can affect the chemical composition or metabolites of grapes and their wines. Grapes grown in three different regions of South Korea were collected and separated into pulp, skin, and seed. The grapes were also vinified after crushing. (1)H NMR spectroscopy with

Metabolomic prediction of treatment outcome in pancreatic ductal adenocarcinoma patients receiving gemcitabine.

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OBJECTIVE Resistance to gemcitabine remains a key challenge in the treatment of pancreatic ductal adenocarcinoma (PDAC), necessitating the constant search for effective strategies for a priori prediction of clinical outcome. While the existing studies focused on aberration of drug disposition genes

GABA enhances physio-biochemical metabolism and antioxidant capacity of germinated hulless barley under NaCl stress.

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The effects of exogenous γ-aminobutyric acid (GABA) on the endogenous GABA metabolism and antioxidant capacity of germinated hulless barley (Hordeum vulgare L.) under NaCl stress were investigated. The results showed that all of the GABA treatments could alleviate the growth inhibition and oxidative

Metabolic, endocrine and haematological responses to intravenous E. coli endotoxin administration in 1-week-old calves.

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Responses to i.v. injected E. coli endotoxin (E), followed by saline infusion, as compared with saline infusion alone, were studied for 24 h in 1-week-old calves. After administration of E, respiratory rate (RR), heart rate (HR), rectal temperature (RT), serum iron, insulin, (I), cortisol and tumor

Coumarin pretreatment alleviates salinity stress in wheat seedlings.

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The potentiality of COU to improve plant tolerance to salinity was investigated. Wheat grains were primed with COU (50 ppm) and then grown under different levels of NaCl (50, 100, 150 mM) for two weeks. COU pretreatment improved the growth of wheat seedling under salinity, relative to COU-untreated

Metabolic fingerprinting analysis of oil palm reveals a set of differentially expressed metabolites in fatal yellowing symptomatic and non-symptomatic plants.

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Oil palm (E. guineensis), the most consumed vegetable oil in the world, is affected by fatal yellowing (FY), a condition that can lead to the plant's death. Although studies have been performed since the 1980s, including investigations of biotic and abiotic factors, FY's cause remains

[Effects of crude toxin from Alternaria alternata on the growth and physiological metabolism of chrysanthemum 'Jinba' seedlings].

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The chrysanthemum black spot caused by Alternaria alternata significantly reduced the quality and yield of chrysanthemum. The crude toxin secreted by A. alternata in the metabolic process have elopathic effects on plants, which is the main pathogenic factor for the occurrence of chrysanthemum black

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