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We investigated the function of monoaminergic neuron in the brainstem by measuring its metabolites using in vivo microdialysis following experimental subarachnoid hemorrhage in rats. Dialysis probe was implanted into the nucleus tractus solitarius (NTS) and continuous perfusion was then started. The
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The nonsteroidal anti-inflammatory drugs (NSAIDs) cover a wide range of selectivity, from the nonselective cyclooxygenase (COX) inhibitors to the preferential COX-2, and the newest coxibs, selective COX-2, with 1000-fold selectivities for COX-2. Coxibs belong to the distinct classes of
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Coronary artery spasm (CAS) is a pathophysiological phenomenon that may cause myocardial infarction and lead to circulatory collapse and death. Aberrant endoplasmic reticulum (ER) stress causes accumulation of misfolding proteins and has been reported to be involved in a variety of vascular
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