port-wine stain/protease

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Inhibitory effect of the transcription factor encoded by the mutant mi microphthalmia allele on transactivation of mouse mast cell protease 7 gene.

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The transcription factor encoded by the mi locus (MITF) is a transcription factor of the basic-helix-loop-helix zipper protein family. Mice of mi/mi genotype express a normal amount of abnormal MITF, whereas mice of tg/tg genotype do not express any MITFs due to the transgene insertional mutation.

[Anti-inflammatory actions of proteases, bromelain, trypsin and their mixed preparation (author's transl)].

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Anti-inflammatory actions of proteases, bromelain (BR), trypsin (TR) and their mixed preparation (KT) were studied mainly in rabbits using various experimental test methods. Inhibitory action of edema formation induced by carrageenin was observed to be dose dependent with oral administrations of KT.

Statistical Approach for Optimization of Physiochemical Requirements on Alkaline Protease Production from Bacillus licheniformis NCIM 2042.

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The optimization of physiochemical parameters for alkaline protease production using Bacillus licheniformis NCIM 2042 were carried out by Plackett-Burman design and response surface methodology (RSM). The model was validated experimentally and the maximum protease production was found 315.28 U using

Antibody-dependent cell-mediated cytotoxicity in humans. III. Effect of protease inhibitors and substrates.

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Different classes of protease inhibitors and substrates were tested for their effect on the ability of human lymphocytes to mediate antibody-dependent cytotoxicity (Ab CMC). All the inhibitors tested (serine esterase inhibitors, chloromethyl ketone derivatives of tosyl-amino acids, synthetic

Purification of the extracellular protease of Bacillus licheniformis and its inhibition by bacitracin.

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Sporulating cells of Bacillus licheniformis excrete three seryl proteases that are of similar size, 28,000 daltons, but of different charge at pH 6. The peptide antibiotic bactracin is released from the cells at the same time and exists, in part, as a bacitracin-protease complex that is stable

Aprotinin effects related to oxidative stress in cardiosurgery with mechanical cardiorespiratory support (CMCS).

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There is evidence to support a relationship between oxidative stress and protease release in "ischemia-reperfusion damage." We have proposed that aprotinin may exert an antioxidant effect. A double blind clinical trial was performed with a control (G-1) and treated (G-2) groups, both submitted to

Inhibition of tobacco etch virus protease activity by detergents.

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Affinity tags such as polyhistidine greatly facilitate recombinant protein production. The solubility of integral membrane proteins is maintained by the formation of protein-detergent complexes (PDCs), with detergent present at concentration above its critical micelle concentration (CMC). Removal of

Aprotinin mediated antioxidant effect in Cardiosurgery with mechanical cardiorespiratory support (CMCS).

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BACKGROUND Aprotinin has been used in cardiosurgery as a hemostatic agent. Considering the implication of oxygen reactive species and proteases in the pathogenesis of Systemic Inflammatory Response Syndrome, we hypothesized that aprotinin may exert an antioxidant effect. This work was designed to

[Association between lysosomal cysteine protease cathepsin's activation and left ventricular function and remodeling in hypertensive heart failure rats].

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OBJECTIVE To observe myocardial cathepsin (Cat) S expression and activity in hypertensive heart failure rats. METHODS The expression and activity of Cat S were determined in the left ventricular (LV) myocardium (LVM) of Dahl salt-sensitive rats fed either a high-salt (HS, 8%) or low-salt (LS, 0, 3%,

Stably transfected antisense granzyme B and perforin constructs inhibit human granule-mediated lytic ability.

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In human NK cells and CTL it has been shown that release of lytic molecules is, at least in part, responsible for the lysis of target cells (TC). Of the various types of molecules thought to be involved in cell-mediated cytotoxicity (CMC), perforin and the serine proteases (granzymes A and B) are

[Effects of soybean isoflavones on RAGE mediated signal transduction in the hippocampus of rats with Alzheimer's disease].

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OBJECTIVE To investigate the effects of soybean isoflavones on receptor for advanced glycation end products (RAGEs) mediated signal transduction in the hippocampus of rats with Alzheimer's disease (AD). METHODS AD rat model was established by bilateral hippocampus injection of amyloid beta25-35

Double enzymatic hydrolysis preparation of heme from goose blood and microencapsulation to promote its stability and absorption.

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Iron deficiency anemia (IDA) is the most common nutritional deficiency worldwide. This deficiency could be solved by preparing stable, edible, and absorbable iron food ingredients using environmentally friendly methods. This study investigated enzymatic hydrolysis and microencapsulation process of

Effects of macromolecular growth substrates on production of extracellular enzymes by Bacillus species in continuous culture.

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Bacillus species 11089 and alkalophilic Bacillus species 11203 were both capable of growth in continuous culture on macromolecular substrates, starch, soybean flour, casein, pectin, polypectate, polygalacturonate and carboxymethylcellulose (CMC) when these were used as the carbon-energy source in a

Development of hypoimmunogenic muffins: batter rheology, quality characteristics, microstructure and immunochemical validation.

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A high demand exists for gluten free and hypoimmunogenic products from gluten sensitive population. The present study focuses on the development of hypoimmunogenic muffins using a combination of the blend (CB) consisting of modified (protease treated) Whole Wheat Flour (WWF) and Pearl Millet Flour

Molecular cloning and characterization of novel cystatin gene in leaves Cakile maritima halophyte.

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Cakile maritima (Brassicaceae) is a halophyte that thrives on dunes along Mediterranean seashores, with high tolerance to salty and dry environments. We have previously shown that there is great morphological and physiological diversity between ecotypes. We investigated the expression of cysteine

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