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Generation of oxygen free radicals in kidney cortex plays an important role in the pathogenesis of gentamicin (GM) nephrotoxicity, and the leaf extract of the medicinal plant Rhazya stricta has been shown to have an anti-oxidant action in rats. Therefore, in the present work we aimed at testing, in
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The nicotine content of cigarettes plays a key role in the pathogenesis of kidney disease. Harmine is a harmal-derived alkaloid with antioxidant properties. This study was designed to evaluate the effects of harmine against nicotine-induced damage to the kidneys of
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