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ribose/inflammation

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Efficacy of Solarplast for Health and Oxidative Stress

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Solarplast is currently sold on the market, which is a unique mixture of antioxidant enzymes and single antioxidant molecules that attack oxidants through chaperone activity. Chaperones, are naturally occurring proteins that assist the non-covalent folding/unfolding and the assembly/disassembly of

Muscle Wasting in Cancer (MWIC)

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Patients: Patients with upper and lower gastrointestinal cancer for planned resectional surgery will be recruited. Patients will be identified by the clinical team at the relevant multidisciplinary team meeting and then approached for study information and consent in the surgical clinic.

Effects of Dietary Amino Acids on Serum and Macrophage Atherogenicity

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Atherosclerosis is the underlying cause of cardiovascular diseases (CVD), the major cause of death worldwide. Atherosclerosis is an inflammatory disease of the arteries in which activated macrophages are abundant in the atherosclerotic lesions. Macrophages play key roles during early atherogenesis.

Citicoline Effect on Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)

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Research design This study is a double blind randomized clinical trial to determine differences in wave amplitude P50 and N95 on pattern ERG examination, visual field defects (LP) with Humphrey HFA (Humphrey Field Analyzer) II-i 750, 24-2 threshold and ganglion cell thickness with OCT CirrusTM

Therapeutic Safety and Efficacy of REP 2139 (REP 9AC') in HBV Infected Patients

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Chronic hepatitis B is a long term condition caused by infection of the body with the hepatitis B virus (HBV). This infection often results in inflammation or scarring of the liver and can eventually lead to liver cirrhosis and liver failure. These infections are also one of the major causes of the

PET Imaging of PARP Activity in Cancer

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Poly(ADP-ribose) polymerase 1 (PARP1) is a deoxyribonucleic acid (DNA) repair enzyme that enables normal cell survival as well as certain cancers. Pharmaceutical companies have invested heavily in PARP1 inhibitor development because these agents can effectively treat certain cancers as single

Continuous Local Anesthetic and Steroid Infusion in Abdominal Surgery

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Anti-inflammatory Effects of Caffeine in Chronic Obstructive Pulmonary Disease (COPD) Subjects

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Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure

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Heart failure (HF) is a complex clinical syndrome and major public health problem claiming the lives of >500,000 per year. It is the leading Diagnosis Related Group (DRG) for hospital discharges in the US. There are approximately 1-3 million admissions annually for acute decompensated heart failure.

Efficacy of FWGE in Combination With Hormone Therapy for the Treatment of Hormone-Refractory Prostate Cancer Patients

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Background and Significance 1. The challenge: Prostate cancer is a major worldwide health problem and is the most frequently diagnosed malignancy in men today. In the United States prostate cancer is the most common malignancy found in men accounting for more than 29% of all diagnosed cancer and
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