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sepsis/hypoxia

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Medical uses of allosteric hemoglobin modifier compounds in patient care

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DESCRIPTION BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention generally relates to using a family of compounds to adjust the allosteric equilibrium of hemoglobin toward a low oxygen affinity state. Moreover, the invention includes several new compounds and contemplates

Prodrug salts

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TECHNICAL FIELD Provided are novel prodrug salts of selective aquaporin inhibitors, e.g., of aquaporin-4 and/or aquaporin-2, of Formula I as described below, their use as pharmaceuticals and pharmaceutical compositions comprising them, and novel intermediates used in and novel processes for their

Prodrug salts

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Log In / Enskri
TECHNICAL FIELD Provided are novel prodrug salts of selective aquaporin inhibitors, e.g., of aquaporin-4 and/or aquaporin-2, of Formula I as described below, their use as pharmaceuticals and pharmaceutical compositions comprising them, and novel intermediates used in and novel processes for their

Devices and methods for using endovascular cooling to treat septic shock and other disorders

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FIELD OF THE INVENTION This invention relates generally to methods for medical treatment and more particularly to the use of endovascular heat exchange devices to treat sepsis, septic shock or other disorders. BACKGROUND OF THE INVENTION It is often desirable to warm or cool all or a portion of the

Devices and methods for using endovascular cooling to treat septic shock and other disorders

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Log In / Enskri
FIELD OF THE INVENTION This invention relates generally to methods for medical treatment and more particularly to the use of endovascular heat exchange devices to treat sepsis, septic shock or other disorders. BACKGROUND OF THE INVENTION It is often desirable to warm or cool all or a portion of the
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