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The edible mushroom Lentinula edodes (shiitake) contains many bioactive compounds. In the present study, we cultivated L. edodes mycelia in solid medium and examined the hot-water extract (L.E.M.) for its suppressive effect on concanavalin A (ConA)-induced liver injury in mice. ConA injection into
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The hot-water extracts of Lentinula edodes mycelia(LEM)contain carbohydrates, proteins, phenolic compounds, and lignin digest, which perform various physiological activities. LEM has hepatoprotective activities in animals with acute liver injury induced by concanavalin A or D-galactosamine.Moreover,
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