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Comparative pharmacokinetics of eight major bioactive components in normal and bacterial diarrhea mini-pigs after oral administration of Gegen Qinlian Decoction.

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Healthy animals are most widely used in current pharmacokinetic(PK) studies. However, neglecting the effects of specific diseases on drug absorption results in the PK parameters of those experiments not accurately reflecting in vivo drug concentration changes during treatment. In this study, an E.

Anti-diarrheal effect of Scutellaria baicalensis is associated with suppression of smooth muscle in the rat colon.

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Scutellaria baicalensis (S. baicalensis) has been used to manage diarrhea, and its anti-inflammatory effects are responsible for anti-diarrheal effects. However, there are no data concerning its direct effect on colonic motility. Therefore, the effects of the major components of S.

Intestinal absorption differences of major bioactive compounds of Gegenqinlian Decoction between normal and bacterial diarrheal mini-pigs in vitro and in situ.
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Intestinal condition plays an important role in drug absorption and metabolism, thus the effects of varied gastrointestinal diseases such as infectious diarrhea on the intestinal function are crucial for drug absorption. However, due to the lack of suitable models, the differences of absorption and

Traditional uses, Clinical studies, and Ten-years Research Progress in Phytochemistry and Pharmacology of the Genus Scutellaria
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Ethnopharmacological relevance: Scutellaria (Lamiaceae), which includes 536 accepted species, is widespread in Europe, North America, East Asia, and South America. Several species are used as traditional medicines for a long history to

Scutellaria baicalensis, the golden herb from the garden of Chinese medicinal plants.
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Scutellaria baicalensis Georgi, or Chinese skullcap, has been widely used as a medicinal plant in China for thousands of years, where the preparation from its roots is called Huang-Qin. It has been applied in the treatment of diarrhea, dysentery, hypertension, hemorrhaging, insomnia, inflammation

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wogonin/gin diare

Comparative pharmacokinetics of eight major bioactive components in normal and bacterial diarrhea mini-pigs after oral administration of Gegen Qinlian Decoction.

Anti-diarrheal effect of Scutellaria baicalensis is associated with suppression of smooth muscle in the rat colon.

Intestinal absorption differences of major bioactive compounds of Gegenqinlian Decoction between normal and bacterial diarrheal mini-pigs in vitro and in situ.

Traditional uses, Clinical studies, and Ten-years Research Progress in Phytochemistry and Pharmacology of the Genus Scutellaria

Scutellaria baicalensis, the golden herb from the garden of Chinese medicinal plants.

Baz done ki pi konplè remèd fèy medsin te apiye nan syans