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OBJECTIVE
Large falls in blood pressure after meals have been demonstrated in fit and frail elderly subjects; these changes may be associated with an increased incidence of stroke. Postprandial falls in BP may be particularly deleterious after acute stroke, when normal baroreflex mechanisms and
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Metabolome profiling is used to identify biomarkers for acute ischemic stroke (AIS). Previous studies compared metabolite profiles in AIS and healthy controls, which did not account for factors that affect metabolome (genetics, medications). This pilot project evaluates the change in
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Starved rats sedated with a neurolept analgesic were subjected to hemorrhagic hypotension while receiving infusions of iso-osmolar and hyperosmolar solutions. The hemorrhage model used resulted in similar residual blood volumes and hematocrits in all groups. The non-metabolizable pentose, xylose,
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