diosgenin/atrophy

A hivatkozás a vágólapra kerül

CikkekKlinikai vizsgálatokSzabadalmak

Válasszon rendezési típust

11 eredmények

Diosgenin restores Aβ-induced axonal degeneration by reducing the expression of heat shock cognate 70 (HSC70).

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

We previously found diosgenin, an herbal drug-derived steroid sapogenin, to be remarkably effective at restoring Aβ-induced axonal degeneration and improving memory function in model of Alzheimer's disease (AD), 5XFAD mouse. In this study, we investigated the downstream signaling of diosgenin and

TCPL drug delivery system: the effects of synthetic DHEA and Diosgenin using an ovariectomized rat model.

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

Dehydroepiandrosterone (DHEA) has been shown in numerous studies to exhibit a host of benefits at the vital and reproductive organ levels. However, the use of naturally occurring DHEA is hindered by its inability to survive the first-pass metabolic process of the liver. One possible alternative

Natural Medicines and Their Underlying Mechanisms of Prevention and Recovery from Amyloid Β-Induced Axonal Degeneration in Alzheimer's Disease

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

In Alzheimer's disease (AD), amyloid β (Aβ) induces axonal degeneration, neuronal network disruption, and memory impairment. Although many candidate drugs to reduce Aβ have been clinically investigated, they failed to recover the memory function in AD patients. Reportedly, Aβ deposition occurred

A pH-Sensitive Prodrug Nanocarrier Based on Diosgenin for Doxorubicin Delivery to Efficiently Inhibit Tumor Metastasis

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

Background: The metastasis, one of the biggest barriers in cancer therapy, is the leading cause of tumor deterioration and recurrence. The anti.-metastasis has been considered as a feasible strategy for clinical cancer management. It is

The use of estrogen, DHEA, and diosgenin in a sustained delivery setting as a novel treatment approach for osteoporosis in the ovariectomized adult rat model.

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

It is well established that the pattern of bone loss from the cortex in osteoporotic bone begins from the endosteal surface of the cortex, where there is enlargement of the medullary canal at the expense of the inner cortex. Bone loss does not occur at the periosteal surface. The objective of the

Neuroprotective effect of diosgenin in a mouse model of diabetic peripheral neuropathy involves the Nrf2/HO-1 pathway.

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes. Diosgenin is a natural steroidal saponin with a variety of beneficial effects, including antidiabetic effects, and is a raw material for the synthesis of carrier hormones. In our study, we

Diosgenin from Dioscorea nipponica ameliorates diabetic neuropathy by inducing nerve growth factor.

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

Diabetic neuropathy is characterized by axonal degeneration, demyelination, and atrophy in association with failed axonal regeneration, remyelination, and synaptogenesis. Recent reports suggest that reduced levels of nerve growth factor (NGF) may play a significant role in the pathogenesis of

Diosgenin-induced cognitive enhancement in normal mice is mediated by 1,25D₃-MARRS.

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

We previously reported that diosgenin, a plant-derived steroidal sapogenin, improved memory and reduced axonal degeneration in an Alzheimer's disease mouse model. Diosgenin directly activated the membrane-associated rapid response steroid-binding receptor (1,25D₃-MARRS) in neurons. However,

Diosgenin-Rich Yam Extract Enhances Cognitive Function: A Placebo-Controlled, Randomized, Double-Blind, Crossover Study of Healthy Adults.

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

Diosgenin, a yam-derived compound, was found to facilitate the repair of axonal atrophy and synaptic degeneration and improve memory dysfunction in a transgenic mouse model of Alzheimer's disease (AD). It was also found to enhance neuronal excitation and memory function even in normal mice. We

Diosgenin is an exogenous activator of 1,25D₃-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice.

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

The aim of this study was to investigate the effects and the mechanism of diosgenin, a famous plant-derived steroidal sapogenin, on memory deficits in Alzheimer's disease (AD) model mice. Diosgenin-treated 5XFAD mice exhibited significantly improved performance of object recognition memory.

Colic caused by Panicum maximum toxicosis in equidae in northern Brazil.

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

In the Amazon region of northern Brazil, Panicum maximum cultivars Mombaça, Tanzânia, and Massai cause severe colic and death in horses and mules. The disease occurs in the rainy season, when sprouting pastures are grazed by equidae. In the 8 separate disease outbreaks studied, a total of 52 out of

Csatlakozzon
facebook oldalunkhoz

Herbal & Natural Medicine

A legteljesebb gyógynövény-adatbázis, amelyet a tudomány támogat

Működik 55 nyelven
A tudomány által támogatott gyógynövényes kúrák
Gyógynövények felismerése kép alapján
Interaktív GPS térkép - jelölje meg a gyógynövényeket a helyszínen (hamarosan)
Olvassa el a keresésével kapcsolatos tudományos publikációkat
Keresse meg a gyógynövényeket hatásuk szerint
Szervezze meg érdeklődését, és naprakész legyen a hírkutatással, a klinikai vizsgálatokkal és a szabadalmakkal

Írjon be egy tünetet vagy betegséget, és olvassa el azokat a gyógynövényeket, amelyek segíthetnek, beírhat egy gyógynövényt, és megtekintheti azokat a betegségeket és tüneteket, amelyek ellen használják.
* Minden információ publikált tudományos kutatáson alapul