Folate / rák

Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

BACKGROUND AND SUMMARY Cancer survival statistics establish the importance of early detection and thorough tumor resection for maximization of patient lifespan. Recent efforts to better achieve these objectives have focused on development of safer, more sensitive, and more discriminating imaging

Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

BACKGROUND AND SUMMARY Cancer survival statistics establish the importance of early detection and thorough tumor resection for maximization of patient lifespan. Recent efforts to better achieve these objectives have focused on development of safer, more sensitive, and more discriminating imaging

Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

BACKGROUND AND SUMMARY Cancer survival statistics establish the importance of early detection and thorough tumor resection for maximization of patient lifespan. Recent efforts to better achieve these objectives have focused on development of safer, more sensitive, and more discriminating imaging

Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

BACKGROUND AND SUMMARY Cancer survival statistics establish the importance of early detection and thorough tumor resection for maximization of patient lifespan. Recent efforts to better achieve these objectives have focused on development of safer, more sensitive, and more discriminating imaging

IgA Fc-folate conjugates, pharmaceutical compositions and methods to treat cancer

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

FIELD OF THE DISCLOSURE The present disclosure provides IgA antibody fragment crystallizable region (Fc)-Folate conjugates that selectively target and kill cancer cells expressing folate receptors. The Fc-Folate conjugates are particularly useful to treat breast cancer, including triple negative

N.sub.3S.sub.1 chelator-folate derivatives, preparation method thereof and composition for diagnosis or treatment of cancer containing the same as an active ingredient

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

CROSS-REFERENCE TO RELATED APPLICATIONS This application claims priority from Korean Patent Application No. 10-2012-0119743, filed on Oct. 26, 2012, and Korean Patent Application No. 10-2013-0127479, filed Oct. 25, 2013, in the Korean Intellectual Property Office, the contents of each of which are

Induction of tumor immunity by variants of folate binding protein

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

FIELD OF THE INVENTION The present invention is directed to the fields of cancer and immunology. Specifically, the present invention is directed to compositions and methods for tumor vaccines directed to tumor antigens and is directed to specific epitopes on these antigens that are recognized by

Induction of tumor immunity by variants of folate binding protein

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

FIELD OF THE INVENTION The present invention is directed to the fields of cancer and immunology. Specifically, the present invention is directed to compositions and methods for tumor vaccines directed to tumor antigens and is directed to specific epitopes on these antigens that are recognized by

Induction of tumor immunity by variants of folate binding protein

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

FIELD OF THE INVENTION The present invention is directed to the fields of cancer and immunology. Specifically, the present invention is directed to compositions and methods for tumor vaccines directed to tumor antigens and is directed to specific epitopes on these antigens that are recognized by

Induction of tumor immunity by variants of folate binding protein

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

FIELD OF THE INVENTION The present invention is directed to the fields of cancer and immunology. Specifically, the present invention is directed to compositions and methods for tumor vaccines directed to tumor antigens and is directed to specific epitopes on these antigens that are recognized by

Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

FIELD OF THE INVENTION This invention relates to novel difluoroglutamic acid conjugates with folates and anti-folates, to the use of these conjugates in the treatment of neoplastic diseases, and to intermediates used in the preparation of the conjugates. BACKGROUND OF THE INVENTION Folates and

Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

FIELD OF THE INVENTION This invention relates to novel difluoroglutamic acid conjugates with folates and anti-folates, to the use of these conjugates in the treatment of neoplastic diseases, and to intermediates used in the preparation of the conjugates. BACKGROUND OF THE INVENTION Folates and

Combination therapy for cancer using HSP27 inhibitor and EGFR tyrosine kinase inhibitors or anti-folates

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

FIELD OF THE INVENTION This application relates to combination therapy for the treatment of cancer using inhibitors of heat shock protein 27 (Hasp 27) and an epidermal growth factor tyrosine kinase inhibitor (EGFR-TKI) such as erlotinib, or antifolates such as pemetrexed. BACKGROUND OF THE

Methods of treating cancer in a patient by administering anti-folate-receptor-1 (FOLR1) antibodies

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

REFERENCE TO A SEQUENCE LISTING SUBMITTED ELECTRONICALLY VIA EFS-WEB The Sequence Listing submitted Mar. 29, 2017, as a text file named "2921.0440004_SequenceListing_ST25," created on Mar. 28, 2017, and having a size of 68,562 bytes, is hereby incorporated by reference pursuant to 37 C.F.R. .sctn.

Folate-conjugated molecules for delivery of toxic small molecule inhibitors to cancer cells and methods of use

Csak regisztrált felhasználók fordíthatnak cikkeket

Belépés Regisztrálás

BACKGROUND Thapsigargin (TG) is a naturally-occurring compound that is highly specific for inhibiting the sarco/endoplasmic reticulum and endoplasmic reticulum Ca.sup.2+-ATPase pump (SERCA). The inventors recently identified TG as a modulator of Notch (Roti G., et al., "Complementary genomic screens

folate/rák

Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology

Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology

Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology

Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology

IgA Fc-folate conjugates, pharmaceutical compositions and methods to treat cancer

N.sub.3S.sub.1 chelator-folate derivatives, preparation method thereof and composition for diagnosis or treatment of cancer containing the same as an active ingredient

Induction of tumor immunity by variants of folate binding protein

Induction of tumor immunity by variants of folate binding protein

Induction of tumor immunity by variants of folate binding protein

Induction of tumor immunity by variants of folate binding protein

Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases

Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases

Combination therapy for cancer using HSP27 inhibitor and EGFR tyrosine kinase inhibitors or anti-folates

Methods of treating cancer in a patient by administering anti-folate-receptor-1 (FOLR1) antibodies

Folate-conjugated molecules for delivery of toxic small molecule inhibitors to cancer cells and methods of use

A legteljesebb gyógynövény-adatbázis, amelyet a tudomány támogat