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glutathione/vérzés

A hivatkozás a vágólapra kerül
Oldal 1 tól től 768 eredmények
The pathogenesis of gastric antral hemorrhage and ulceration is unclear. This paper first proposes that antral hemorrhagic ulcers produced in rats are associated with attenuation of defensive parameters (such as mucosal glutathione levels and histamine release, as well as aggravation of aggressive

Glutathione peroxidase 1 C593T polymorphism is associated with lobar intracerebral hemorrhage.

Csak regisztrált felhasználók fordíthatnak cikkeket
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BACKGROUND Oxidative stress plays an important role in vascular pathology and contributes to the pathophysiology of primary intracerebral hemorrhage (PICH). Glutathione peroxidase 1 (GPX1) is a key enzyme of the antioxidant system. Here, we investigated whether a functional C593T polymorphism of

Vasospasm after subarachnoid hemorrhage in haptoglobin 2-2 mice can be prevented with a glutathione peroxidase mimetic.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
Vasospasm after subarachnoid hemorrhage (SAH) is attributable to inflammation and oxidative stress associated with extracellular hemoglobin (Hb). Haptoglobin (Hp) binds free Hb and the Hp-Hb complex is cleared by macrophages, and the Hp-2 isoform of Hp is associated with more oxidative stress and

Effect of haemorrhage on hepatic glutathione concentration: an experimental study in the pig.

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Depletion in the hepatic concentration of reduced glutathione (GSH) may potentiate liver injury resulting from toxic metabolites. Patients who have had severe haemorrhage frequently develop hepatic dysfunction and we have shown that the hepatic GSH level is decreased in these patients. The present
The pathogenic mechanisms underlying betel quid chewing (BQC)-induced gastric haemorrhagic ulcer are totally unknown. This study first demonstrated that BQC produced gastric haemorrhagic ulcer via oxidative stress that could be protected by lysozyme chloride and glutathione in rats. Male Wistar rats

Epinephrine protects against severe acute gastric bleeding in rats: role of nitric oxide and glutathione.

Csak regisztrált felhasználók fordíthatnak cikkeket
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The aim of this study was to examine the effect of the systemic administration of epinephrine against severe acute gastric bleeding in rats. Epinephrine decreased gastric hemorrhage not only before but also after lipopolysaccharide-induced severe acute gastric bleeding. Epinephrine ameliorated

Glutathione peroxidase and subarachnoid hemorrhage: implications for the role of oxidative stress in cerebral vasospasm.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
OBJECTIVE Worldwide, cerebral vasospasm after subarachnoid hemorrhage (SAH) has an estimated morbidity and mortality of 1.2 million annually. While it has long been suspected that reactive oxygen species play a major role in the etiology of cerebral vasospasm after SAH, promising results in animal

[The effect of cobavit on glutathione system in patients with bleeding gastroduodenal ulcer].

Csak regisztrált felhasználók fordíthatnak cikkeket
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Index of glutathione system studied in 20 healthy persons (KG-1), in 20 with non-complicated duodenal ulcer (KG-2), in 210 patients with bleeding gastroduodenal ulcer, in 77 in early period after different operations. Results obtained showed that ulcer disease, complicated with bleeding was

Glutathione synthetase deficiency associated with antenatal cerebral bleeding.

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We present a newborn with glutathione synthetase deficiency and intracranial haemorrhages. Because the latter are rare in term newborns a possible relationship with glutathione synthetase deficiency will be discussed.

Comparision of uroprotective activity of reduced glutathione with mesna in ifosfamide induced hemorrhagic cystitis in rats.

Csak regisztrált felhasználók fordíthatnak cikkeket
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BACKGROUND Ifosfamide (IFO) is widely used DNA-alkylating agents in cancer chemotherapy for management of solid tumors and hematological malignancies. However, hemorrhagic cystitis limits the use of IFO. OBJECTIVE To compare the efficiency of reduced glutathione with 2-Mesna in reducing Ifosfamide
OBJECTIVE To investigate the glutathione concentrations in gastric mucosa from patients with acute gastric bleeding related to nonsteroidal anti-inflammatory drugs (NSAIDs), and to test the influence of nutritional status on mucosal glutathione. Glutathione protects the gastrointestinal mucosa

Gastric mucosal injury caused by hemorrhagic shock and reperfusion: protective role of the antioxidant glutathione.

Csak regisztrált felhasználók fordíthatnak cikkeket
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Oxygen free radicals have been implicated as mediators of gastric mucosal injury caused by ischemia/reperfusion. We investigated the role of exogenous and endogenous glutathione (reduced glutathione, GSH) in gastric mucosal injury associated with hemorrhagic shock and reperfusion. Mucosal GSH

Importance of histamine, glutathione and oxyradicals in modulating gastric haemorrhagic ulcer in septic rats.

Csak regisztrált felhasználók fordíthatnak cikkeket
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1. The ulcerogenesis of gastric haemorrhagic damage during sepsis is unclear. The present study first proposes that gastric haemorrhagic ulcer is modulated by mucosal glutathione, histamine and oxyradicals in lipopolysaccharide (LPS)-induced sepsis in rats. The protective effects of several drugs on
BACKGROUND Malondialdehyde (MDA) is a marker of lipid peroxidation. Glutathione peroxidase (GPX) and superoxide dismutase (SOD) are the main enzymes responsible for the detoxification of superoxide anion. The aim was to assess whether serum MDA, erythrocyte GPX, and erythrocyte SOD levels altered

Amifostine and glutathione prevent ifosfamide- and acrolein-induced hemorrhagic cystitis.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
BACKGROUND Ifosfamide (IFS) is an antineoplastic alkylating agent whose major side effect is hemorrhagic cystitis (HC). This toxicity is attributed to the renal excretion of acrolein (ACR), a highly urotoxic IFS metabolite. Despite the clinical use of mesna to prevent HC, a significant percent (
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