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hepatic encephalopathy/protease

A hivatkozás a vágólapra kerül
11 eredmények

Lack of therapeutic effects of gabexate mesilate on the hepatic encephalopathy in rats with acute and chronic hepatic failure.

Csak regisztrált felhasználók fordíthatnak cikkeket
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OBJECTIVE Inflammation plays a pivotal role in liver injury. Gabexate mesilate (GM, a protease inhibitor) inhibits inflammation by blocking various serine proteases. This study examined the effects of GM on hepatic encephalopathy in rats with acute and chronic liver failure. METHODS Acute and
This study was designed to evaluate the hepato and neuroprotective activity of Daflon and low-dose γ radiation on thioacetamide (TAA)-induced liver damage and hepatic encephalopathy (HE) in rats. Effect of daily Daflon treatment (100 mg/kg body weight, Per OS (p.o.) for consecutive 3 days) and/or

Effect of three antibacterial drugs in lowering blood & stool ammonia production in hepatic encephalopathy.

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Neomycin (700 mg/8 h), ampicillin (500/6 h) and metronidazole (400 mg/8 h), were compared for their effect, on oral administration for 4 days, in reducing blood ammonia in 27 patients with stable chronic liver disease. It was found that there was 38.2, 38.5 and 8.7 m mol/litre mean reduction in
OBJECTIVE Many patients continue to die due to the rapid development of cerebral edema and/or multiple organ failure prior to receiving a liver transplantation. METHODS We investigated the prognostic factors associated with 1-week fatal outcomes after the diagnosis of fulminant hepatic failure,

BCA, HGF, and proteasomes.

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This is my reminiscent essay of my research life, but not a review article of specific subject. We found in the 1960s that BCAs (the branched chain amino acids, valine, leucine, and isoleucine) are unique in being the least metabolized amino acids in liver due to low activity of their transaminase.

Cirrhosis in hepatitis C virus-infected patients: a review for practitioners new to hepatitis C care.

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Treatment of hepatitis C virus (HCV)-infected patients with cirrhosis remains challenging. Biopsy to stage liver fibrosis remains the standard for identifying cirrhosis, although the noninvasive technique of transient elastography is promising in this regard. Cirrhosis is categorized as compensated

[Financial burden of hepatitis C infection and its treatment].

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The worldwide prevalence of hepatitis C infection is 2-3%. In addition to its individual consequences, it generates huge financial impact on national level. In particular, lack of recognition or late diagnosis of the disease is associated with high rate of liver cirrhosis related complications

[Hereditary alpha 1-antitrypsin deficiency and infantile cirrhosis of the liver].

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A report on 9 cases of infantile hepatopathy and cirrhosis of the liver respectively in cases of hereditary autosome-recessive alpha 1-antitrypsin deficiency (alpha 1-ATM). The genetic variants of the serum-protease-inhibitor (Pi) alpha 1-antitrypsin (alpha 1-AT) were examined by means of

[Therapy of aminoacid and protein metabolism disturbances in liver disease (author's transl)].

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1. The role of the liver in synthesis and metabolism of proteins, in the metabolism of certain aminoacids, and in urea synthesis is described. 2. In the liver disease protein synthesis may be reduced. The activity of lysosomal proteases is enhanced during acute hepatitis and in cirrhosis. Diseases
Rifaximin, a topical derivative of rifampin, inhibited urease production and other virulence factors at sub-MIC concentrations in strains involved in hepatic encephalopathy and the expression of methicillin resistance in Staphylococcus aureus. In particular, urease production was affected in all

Role of Matricellular Proteins in Disorders of the Central Nervous System.

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Matricellular proteins (MCPs) are actively expressed non-structural proteins present in the extracellular matrix, which rapidly turnover and possess regulatory roles, as well as mediate cell-cell interactions. MCPs characteristically contain binding sites for other extracellular proteins, cell
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