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hepatoblastoma/elhízás

A hivatkozás a vágólapra kerül
11 eredmények
BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is associated with obesity, insulin resistance and hepatic steatosis. Non-alcoholic steatohepatitis (NASH) is a serious consequence of NAFLD where chronic tissue damage and inflammation result in fibrosis which may progress to cirrhosis.

[Retrospective analysis of maternal and infant birth features of hepatoblastoma patients].

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
OBJECTIVE To explore the risk factors for hepatoblastoma. METHODS A case-cohort study using Logistic regression multiple variables analysis of medical record data sets was conducted to examine infant and perinatal risk factors for hepatoblastoma. RESULTS Birth weight less than 1,000 g was associated

Effects of octreotide on hepatic glycogenesis in rats with high fat diet‑induced obesity.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
Reduced hepatic glycogenesis is one of the most important causes of metabolic abnormalities in non‑alcoholic fatty liver disease. Octreotide, a somatostatin analogue, has been demonstrated to promote weight loss and improve metabolic disorders in mice with high fat diet (HFD)‑induced obesity.

Plasma total and glycosylated corticosteroid-binding globulin levels are associated with insulin secretion.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
In humans, steroid hormones circulate in the blood mainly bound to specific steroid transport proteins, namely corticosteroid-binding globulin (CBG) for cortisol and sex hormone-binding globulin (SHBG) for testosterone and estradiol. The binding activities of these proteins are believed to modulate
BACKGROUND Free fatty acids (FFA) and tumor necrosis factor alpha (TNF-alpha) have been implicated in the pathogenesis of many obesity-related metabolic disorders. When human hepatoblastoma cells (HepG2) were exposed to different types of FFA and TNF-alpha, saturated fatty acid was found to be
Tumour necrosis factor-alpha (TNF-alpha) plays a key role in orchestrating the complex events involved in inflammation and immunity. Accordingly, TNF-alpha has been implicated in a wide range of autoimmune and infectious diseases, but also in conditions such as obesity and insulin resistance. The

Possible mechanism of action of AE0047, a calcium antagonist, on triglyceride metabolism.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
We evaluated the effect of AE0047, a dihydropyridine-type calcium antagonist, on the plasma lipid levels of obese Zucker rats. In rats treated orally with 3 to 10 mg/kg/day AE0047 for 7 days, plasma triglyceride (TG) and TG-rich lipoprotein levels dose-dependently decreased, whereas those of

Trends and Patterns of Primary Hepatic Carcinoma in Saudi Arabia.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
Primary hepatic carcinoma (PHC) is the 4th most common malignancy among males at King Faisal Specialist Hospital and Research center (KFSH & RC) and in Saudi Arabia. There has been a steady increase in the number of PHC cases since 1975 at KFSH & RC and the burden of hepatic

Ginsenoside Mc1 improves liver steatosis and insulin resistance by attenuating ER stress.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
Ginsenoside, a major pharmacologically active ingredient in ginseng, has been known to exhibit beneficial properties such as antioxidant and anti-inflammatory effects. Ginsenoside compound Mc1 is one of the newly identified de-glycosylated ginsenosides. Endoplasmic reticulum (ER)

Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone-binding globulin gene.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
The liver produces plasma sex hormone-binding globulin (SHBG), which transports sex steroids and regulates their access to tissues. In overweight children and adults, low plasma SHBG levels are a biomarker of the metabolic syndrome and its associated pathologies. Here, we showed in transgenic mice

Molecular Mechanism of TNFα-Induced Down-Regulation of SHBG Expression.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
The reason why obesity (a chronic low-grade inflammatory disease) is associated with low levels of sex hormone-binding globulin (SHBG) remains to be elucidated. The present study provides evidence that TNFα (a proinflammatory cytokine increased in obesity) reduces SHBG production by human HepG2
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