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Oldal 1 tól től 36 eredmények
Lanthanum probe studies of cellular pathophysiology induced by hypoxia in isolated cardiac muscle.
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Belépés Regisztrálás
This study was undertaken to evaluate directly the relationship between evolution of irreversible myocardial injury induced by hypoxia in an isolated papillary muscle preparation and the development of pathophysiological alterations related to severely impaired membrane function. An ionic lanthanum
Effects of nitroglycerin, dipyridamole, nifedipine, verapamil and diltiazem on canine coronary arterial rings contracted with 5-hydroxytryptamine and anoxia.
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Anoxia has been shown to potentiate the constrictor effects of 5-hydroxytryptamine (5HT) in isolated vascular tissue. In the present study, canine coronary arterial rings were incubated with various treatments and exposed to 5HT (4 X 10(-7) M) and anoxia (95% N2 and 5% CO2). Developed tension was
Centrilobular liver necrosis induced by hypoxia in chronic ethanol-fed rats.
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Rats fed ethanol from 21 to 130 days were subjected to one or more episodes of hypoxia (6% O2) in order to determine if ethanol predisposed to centrilobular liver necrosis induced by hypoxia. Pair-fed control rats were fed the diet regimen in parallel with the ethanol-fed rats through an indwelling
Dissociation of K+-induced tension and cellular Ca2+ retention in vascular and intestinal smooth muscle in normoxia and hypoxia.
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In experiments on smooth muscle preparations of rabbit aorta and guinea pig taenia coli, replacement of the external Na+ with K+ produced sustained contraction. When external K+ concentration was increased, cellular Ca2+ retention as measured by a modified lanthanum technique increased. However,
Inhibition of the Na(+)-Ca++ exchanger enhances anoxia and glucopenia-induced [3H]aspartate release in hippocampal slices.
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The aim of the present study was to investigate the possible role played by the Na(+)-Ca++ exchange system in the modulation of D-[3H]aspartate release induced by anoxia and glucopenia from hippocampal slices. When hippocampal slices were exposed to anoxic and glucopenic conditions (oligomycin +
[Pathways of lanthanum ion transport across the posterior epithelium of the cornea in rabbits].
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Morphological estimation of the barrier-transport properties of the posterior epithelium in the donor cornea has been performed in the most early time of fanoxic lesions of the cells. Ionized lanthanum, as an effective inhibitor of oxidative phosphorylation and simultaneously--as a marker of
Calcium flux measurements during hypoxia in cultured heart cells.
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We tested the hypothesis that cultured chick embryo ventricular cells grown in monolayer could be used to study calcium fluxes across the myocardial sarcolemmal membrane during simulated ischemia. A specially adapted anaerobic chamber allowed the exposure of heart cells to profound hypoxia (PO2 less
[Protective effects of selenium on ultrastructural changes in heart muscles with experimental free-glucose and anoxia in organ culture].
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Fetal hearts taken from the 16th to 18th day of pregnant mice were cultured in MEM + 0.5 microgram/ml of sodium selenite [Na2SeO3] (MEMS), and in MEM alone with oxygen for 24 hours, and then the two groups of hearts were exposed to 10, 15, 20, 30, 40, 60 min and a long term of anoxia in glucose-free
Tension maintenance, calcium content and energy production of the taenia of the guinea-pig caecum under hypoxia.
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Belépés Regisztrálás
When potassium (45.4 mM) was applied to isolated taenia of guinea-pig caecum, the muscle developed a rapid phasic and sustained tonic tension during aerobic conditions bubbled with 95% O2:5% CO2. Under hypoxic conditions bubbled with 95% N2:5% CO2, the taenia lost its ability to respond to high
Pharmacological evidence that the activation of the Na(+)-Ca2+ exchanger protects C6 glioma cells during chemical hypoxia.
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1. In C6 glioma cells exposed to chemical hypoxia a massive release of lactate dehydrogenase (LDH) occurred at 3 and 6 h, coupled with an increased number of propidium-iodide positive dead cells. 2. Extracellular Na+ removal, which activates the Na(+)-Ca2+ exchanger as a Na+ efflux pathway and
Effect of hypoxia and reoxygenation on the isolated rabbit heart determined by monoclonal antimyosin antibody uptake.
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OBJECTIVE
The aim was to examine the effect of hypoxia and reoxygenation upon the isolated rabbit heart, and to determine whether or not irreversible tissue injury develops in association with the reintroduction of molecular oxygen to the previously hypoxic heart.
METHODS
Isolated rabbit hearts
Anoxia-induced contraction of guinea-pig taenia coli in a glucose-free medium.
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Belépés Regisztrálás
The smooth muscle of guinea-pig taenia coli contracted upon exposure to an oxygen deprived glucose-free medium aerated with 95% N2 and 5% CO2. An aeration using 95% O2 and 5% CO2 resulted in an immediate relaxation of the contraction. The anoxia-induced muscle contractions were diminished when the
Ion-assisted deposition of lanthanum fluoride thin films.
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Belépés Regisztrálás
Ion-assisted deposition has been used to deposit lanthanum fluoride thin films with near-unity film packing densities and no significant increase in absorption. Rutherford backscattering analysis has determined the effect of ion bombardment on the film stoichiometries including the degree of
O2 availability modulates transmembrane Ca2+ flux via second-messenger pathways in anoxia-tolerant hepatocytes.
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Transmembrane Ca(2+)-flux was studied from single isolated turtle hepatocytes by using a noninvasive Ca(2+)-selective self-referencing microelectrode. Cells in Ca(2+)-reduced culture medium demonstrated a vanadate- and lanthanum-inhibitable Ca(2+)-efflux of 4 x 10(-17) mol Ca2+. microns-2. s-1
Vascular membrane permeability during hypoxia.
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Belépés Regisztrálás
Extracellular space measurements using radioisotope markers (35S-sulphate and 14C-sorbitol) and ultrastructural examination of lanthanum distribution have been carried out on two vascular tissues (aorta, portal vein) exposed to normoxic and hypoxic media to see if hypoxia is associated with membrane
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