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polyphenol/sarcoma

A hivatkozás a vágólapra kerül
CikkekKlinikai vizsgálatokSzabadalmak
Oldal 1 tól től 18 eredmények
Pinecone polyphenols are bioactive dietary constituents that enhance health and help prevent and treat cancer through improving antioxidant and immunoregulatory activities. This study was designed to investigate the antitumor, antioxidant and immunoregulatory activities of the 40% ethanol eluent of
The cytostatic effects of the polyphenol curcumin and Viscum album extract (VAE) were assessed in soft-tissue sarcoma (STS) cells. Eight human STS cell lines were used: fibrosarcoma (HT1080), liposarcoma (SW872, T778, MLS-402), synovial sarcoma (SW982, SYO1, 1273), and malignant fibrous histiocytoma

Anti‑proliferative activity of epigallocatechin‑3‑gallate and silibinin on soft tissue sarcoma cells.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
Disseminated soft tissue sarcomas (STS) present a therapeutic dilemma. The first-line cytostatic doxorubicin demonstrates a response rate of 30% and is not suitable for elderly patients with underlying cardiac disease, due to its cardiotoxicity. Well‑tolerated alternative treatment options,

Tea polyphenol protects against cisplatin-induced meiotic defects in porcine oocytes.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
DDP (cisplatin), a DNA cross-linking agent, is one of the most common chemotherapeutic drugs that have been widely used in the treatment of sarcomas and germ cell tumors. DDP treatment exhibits severe side effects including renal toxicity, ototoxicity and embryo-toxicity. Women of reproductive age

(-)-Epigallocatechin-3-gallate alleviates doxorubicin-induced cardiotoxicity in sarcoma 180 tumor-bearing mice.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
OBJECTIVE (-)-Epigallocatechin-3-gallate (EGCG), a major green tea polyphenol compound, plays an important role in the prevention of cardiovascular disease and cancer. The present study aimed to investigate the effects of EGCG on doxorubicin (DOX)-induced cardiotoxicity in Sarcoma 180 (S180)

Targeting tumor ubiquitin-proteasome pathway with polyphenols for chemosensitization.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
The development of tumor drug resistance is one of the biggest obstacles on the way to achieve a favorable outcome of chemotherapy. Among various strategies that have been explored to overcome drug resistance, the combination of current chemotherapy with plant polyphenols as a chemosensitizer has

Mechanisms of inhibition of tumor angiogenesis and vascular tumor growth by epigallocatechin-3-gallate.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
OBJECTIVE Green tea consumption has been linked to a reduced occurrence of some tumor types. Current data indicate that the principal mediator of this chemopreventive effect is epigallocatechin-3-gallate (EGCG), the most abundant polyphenol found in dried tea leaves. Here, we examined the effects of

Influence of Echinacea purpurea intake during pregnancy on fetal growth and tissue angiogenic activity.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
The process of angiogenesis and control of blood vessels sprouting are fundamental to human health, as they play key roles in many physiological and pathological conditions. Intake of different pharmaceuticals with antiangiogenic activity by pregnant women may lead to severe developmental

In Vitro and In Vivo Immunomodulator Activities of Allium sativum L.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
Allium Sativum L. (garlic), which is a species of the onion family, Alliaceae, is one of the most used plants in traditional medicine worldwide. More than 200 chemicals with diverse properties have been found in garlic extracts. Several garlic compounds were suggested to be efficient in improving

Can propolis and caffeic acid phenethyl ester be promising agents against cyclophosphamide toxicity?

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
Propolis is a mixture having hundreds of polyphenols including caffeic acid phenethyl ester (CAPE). They have been using in several medical conditions/diseases in both in vitro and in vivo experimental setup. Cyclophosphamide (CP) has been used to treat a broad of malignancies including Hodgkin's

Green tea, red wine and lemon extracts reduce experimental tumor growth and cancer drug toxicity.

Csak regisztrált felhasználók fordíthatnak cikkeket
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OBJECTIVE To evaluate antitumor effect of plant polyphenol extracts from green tea, red wine lees and/or lemon peel alone and in combination with antitumor drugs on the growth of different transplanted tumors in experimental animals. METHODS Green tea extract (GTE) was prepared from green tea

Green tea catechins (EGCG and EGC) have modulating effects on the activity of doxorubicin in drug-resistant cell lines.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
The chemopreventive effect of polyphenols from green tea [e.g. (-)-epigallocatechin gallate (EGCG) and (-)-epigallocatechin (EGC)] against cancer has been demonstrated in several studies. The aim of this investigation was to prove whether these compounds modulate the activity of antineoplastic

Flavanone metabolism in healthy and tumor-bearing rats.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
Flavanones, the main polyphenols of citrus fruits, are thought to contribute to the protective effects of these fruits against cardiovascular diseases and cancer. The metabolism of naringin (naringenin 7-O-neohesperidoside) is studied here in healthy (sham-operated, ShO) and tumor-bearing (TuB)

Curcumin is an APE1 redox inhibitor and exhibits an antiviral activity against KSHV replication and pathogenesis.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
Curcumin, a polyphenol, is the main bioactive compound in dietary spice turmeric curcuma longa. It possesses anti-inflammatory, anti-oxidant and anti-neoplastic properties and shows potentials in treating or preventing particular diseases such as oxidative and inflammatory conditions, metabolic

Impact of Natural Compounds on DNA Methylation Levels of the Tumor Suppressor Gene RASSF1A in Cancer.

Csak regisztrált felhasználók fordíthatnak cikkeket
Belépés Regisztrálás
Epigenetic inactivation of tumor suppressor genes (TSG) is a fundamental event in the pathogenesis of human cancer. This silencing is accomplished by aberrant chromatin modifications including DNA hypermethylation of the gene promoter. One of the most frequently hypermethylated TSG in human cancer
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