The patient in this arm will be ask to stop P2Y12 inhibitor before dental procedure, 5 days for clopidogrel and ticagrelol and 7 days for prasugrel.

The patient in this arm will continue dual anti platelet until the date of dental procedure.

Dental Diseases

Antiplatelet Agents

Antiplatelet Drugs

The patient s in experimental arm will not be ask to stop P2Y12 inhibitor such as Clopidogrel, Prasugrel or Ticagrelor

Clopidogrel

Continue vs. Stop P2Y12 Inhibitor on Bleeding in Patient Receiving DAPT Undergoing Dental Procedure.

Effect of Continue vs. Stop P2Y12 Inhibitor on Bleeding in Patient Receiving Dual-antiplatelet Therapy Undergoing Dental Procedure.

Observed bleeding at 30 minute after finish dental procedure for 30 minute.

Observed severe bleeding at subacute to late phase after dental procedure.

Kultida Lertthanaphol

Cardiology Unit

Chiang Mai University

The dentist will be blind wheater the patient takes DAPT or not.

Group II patients will receive local anesthetic infiltration in two injections on each side of the face at the maxillary and infra-orbital areas and the remaining injections are placebo (saline).

Group V patients will receive local anesthesia in five injections on each side of the face at the infra-orbital area, supratrochlear area, medial to the medial canthus, nasal still and anterior septum. The remaining maxillary injection is placebo.

Submucosal Resection of the Nasal Septum (SMR)

Local anesthetic infiltration in two injections on each side of the face at the maxillary and infra-orbital areas.

suprazygomatic maxillary area infiltration

The remaining injections at supratrochlear area, medial to the medial canthus, nasal still and anterior septum are placebo (saline)

non-suprazygomatic maxillary area placebo

Local anesthetic infiltration in five injections on each side of the face at the infra-orbital area, supratrochlear area, medial to the medial canthus, nasal still and anterior septum.

non-suprazygomatic maxillary area infiltration

The remaining maxillary injection is placebo.

suprazygomatic maxillary area placebo

Makassed General Hospital

Four vs. Ten Local Anesthetic Injections for SMR

Effectiveness of Four Versus Ten Local Anesthetic Injections for Post-submucosal Resection Pain Relief: a Randomized, Double Blinded Clinical Trial

Numeric Rating Scale will be used to measure postoperative pain

Patients' satisfaction is based on their postoperative comfort determined by their feeling of pain, headache and PONV. It will be measured using four point scale (very satisfied, satisfied, little satisfied or dissatisfied)

Surgeon satisfaction is based on intraoperative hemodynamic stability of the patient and bleeding. Postoperative surgeon satisfaction is dependent on patients' feeling of pain (especially upon pack removal), bleeding and number of phone calls made to the surgeon. It will be assessed using four point scale (very satisfied, satisfied, little satisfied or dissatisfied)

Zoher Naja

Chairperson of Anesthesia and Pain Management Department

Impacted Third Molar Tooth

capsules contain 500mg Ginger powder,every 6hours,for 5 days

Ginger powder

capsules of Ibuprofen 400 mg, every 6 hours for 5 days

Ibuprofen

placebo

Qazvin University of Medical Sciences

University of Medical Science

Anti Inflammatory and Analgesic Effect of Ginger Powder in Dental Pain Model

Comparison of The Anti Inflammatory and Analgesic Effect of Ginger and Ibuprofen in Post Surgical Pain Model; a Randomized,Placebo-controlled,Double-blind Clinical Trial

Using standard calipers, cheek thickness will be measured from the lingual aspect of the mid-portion of the crown of the mandibular 1st molar (on the same side) to the tangent of the skin of the cheek.

A venous blood sample (approximately 4 ml, 2ml for CBC check up and 2 ml for CRP concentration) will be collected to quantitatively assess the CRP concentration after surgery and the second sample will be collected 72 hours postoperatively

using 100mmVAS scale,at 1 hour intervals in the first 12 hours following the surgery and every 6 hours until day 5.

assessed by measuring the distance between the upper and lower central incisal edges at maximal mouth opening on days 0 (baseline) and 1,3 and 5 post operatively.

toothache/vérzés

Continue vs. Stop P2Y12 Inhibitor on Bleeding in Patient Receiving DAPT Undergoing Dental Procedure.

Four vs. Ten Local Anesthetic Injections for SMR

Anti Inflammatory and Analgesic Effect of Ginger Powder in Dental Pain Model

A legteljesebb gyógynövény-adatbázis, amelyet a tudomány támogat