[Chemical constituents of antibacterial activity fraction of Angelica polymorpha].

OBJECTIVE

To study chemical constituents of antibacterial activity fraction of Angelica polymorpha.

METHODS

Compounds were isolated by repeatedly silica gel column chromatography and recrystallization. Their structures were identified by physical and chemical evidences and spectral methods.

RESULTS

Seven compounds were obtained from the antibacterial activity fraction, their structures were elucidated as: bisabolangelone(I), isoimperatorin (II), oxypeucedanine(III), isooxypeucedanine(IV), oxypeucedanin hydrate(V), bergapten(VI), pabulenol(VII).

CONCLUSIONS

Bisabolangelone(I) is obtained from this plant for the first time. Compound (II)-(VII) belong to linear furanocourmarins.