[The protease-antiprotease system in pathogenesis of transient arthritis of a single joint in children].

In 35 patients with transient arthritis of a single joint, levels of alpha-1-antitrypsin were determined in the serum in the acute stage of the disease, the recovery period, and the control group. The results were compared. Determination was that the results of examination have indicated a markedly increased level of carried out by the use of M-Partigen, immunodiffusive plates by the Mancini me-alpha-1-antitrypsin in the serum in children in the acute period of this disease and a significant decrease of its level in the period of subsidence of the clinical symptoms in comparison with the control group. The changes in the level of this enzyme indicate disturbance of protease-antiprotease balance in pathogenesis of this disease.