[The use of moderate neurovegetative adrenergic inhibition together with anticoagulants in patients with acute cholecystitis].

The studies have been performed in 178 patients during and after surgery on the biliary ducts. The patients developed marked hyper-reaction of the sympathoadrenal system, total and regional hemodynamic disturbances, hypoxia, disorders in redox processes and blood viscosity and hypercoagulation. To prevent and eliminate the disorders observed small doses of ganglioblockers, alpha- and beta-blockers in combination with heparin were used during surgery and in the earliest postoperative period. As a result hyper-reaction of the sympathoadrenal system was considerably reduced, total and regional hemodynamic parameters were improved, hypoxia was attenuated, redox processes were activated, hypercoagulation decreased and blood viscosity was improved. Lethality in this group decreased from 7.9% to 1.1%. The above technique of neurovegetative adrenergic inhibition and heparinization enhanced adaptation capacities of the body to surgical intervention and improved the results of surgical treatment of patients with acute cholecystitis.