Each subject will receive 532 nm KTP laser treatment for their lower extremity spider veins

532 nm KTP Laser Treatment

Sex: Female, Male

Region of Enrollment

The Fitzpatrick Skin Type is a skin classification system based on color, genetics and reaction to sun exposure. Types range from the I to VI, where type I represents very fair-skinned individuals and type VI represents very dark-skinned individuals.

Fitzpatrick Skin Type

A panel of independent physicians will assess before and after digital photographs of each treated area. The physicians will be blinded to the treatment parameters and to the temporal order of the before and after photographs. Each independent physician will be asked to select the baseline photograph for each treated area and then rate the degree of improvement using the following scale:
0 = No Improvement (0%)
1 = Mild Improvement (< 25%)
2 = Moderate Improvement (26 to 50%)
3 = Significant Improvement (51 to 75%)
4 = Very Significant Improvement (76 to 100%)

Mean Improvement of Lower Extremity Spider Veins Based on Blinded Photo Assessments

The panel of independent physicians will be asked to select the baseline photograph for each treated area and then rate the degree of improvement using the following scale:
0 = No Improvement (0%)
1 = Mild Improvement (< 25%)
2 = Moderate Improvement (26 to 50%)
3 = Significant Improvement (51 to 75%)
4 = Very Significant Improvement (76 to 100%)

The Investigator will perform the Physician's Global Assessment of the degree of improvement for each treated area of the subject's lower extremity spider veins using the following scale:
0 = No Improvement (0%)
1 = Mild Improvement (< 25%)
2 = Moderate Improvement (26 to 50%)
3 = Significant Improvement (51 to 75%)
4 = Very Significant Improvement (76 to 100%)

Percent of Subjects With "Significant" or "Very Significant" Improvement in Lower Extremity Spider Veins, as Assessed by the Treating Investigator.

Subjects will be asked to rate the improvement of each treated area of their lower extremity spider veins as compared to baseline using the following scale:
0 = No Improvement (0%)
1 = Mild Improvement (< 25%)
2 = Moderate Improvement (26 to 50%)
3 = Significant Improvement (51 to 75%)
4 = Very Significant Improvement (76 to 100%)

Percent of Subjects With "Significant" to "Very Significant" Improvement of Lower Extremity Spider Veins, as Assessed by Subject.

Subjects will assess their satisfaction with the procedure and with the improvement in lower extremity spider veins at twelve weeks post final laser treatment based using the following scale:
1 = Very Much Not Satisfied
2 = Not Satisfied
3 = Somewhat Satisfied
4 = Satisfied
5 = Very Much Satisfied

Percent of Subjects Satisfied With Improvement of Treated Spider Veins.

Subjects will be asked to rate the average pain experienced during laser treatments using the 0-10 numeric pain rating scale (0 = no pain to 10 = worst possible pain).

Mean Pain Score Associated With Laser Treatment.

Mean Pain Score Associated With Laser Treatment

Overall Study

Eric F. Bernstein, M.D., M.S.E.

Telangiectasis

Spider Veins

The 532 nm KTP Excel V laser treatment parameters to be used in this study are as follows:
Spot Size: 5 mm
Fluence: 13-15 J/cm2
Pulse Duration: 40 ms
Epidermal contact-cooling: 5° Celsius

telangiectasis/կալիում

Treatment of Lower Extremity Spider Veins With Excel V

Բժշկական դեղաբույսերի ամենալավ տվյալների շտեմարանը, որին աջակցում է գիտությունը