[Clinical trial of cellulose in treatment of functional constipation in children].
Kata kunci
Abstrak
OBJECTIVE
To study the efficacy and safety of cellulose for the treatment of functional constipation in children.
METHODS
A prospective, self-controlled, clinical trial using cellulose was conducted for 2 weeks in 34 children with functional constipation. The constipation symptoms and the characteristics of feces after the treatment were observed.
RESULTS
The characteristics of feces and the constipation symptoms were improved significantly after the treatment. The total efficacy rate was 37% 3 days after treatment, 87% 7 days after treatment and 90% 14 days after treatment. The satisfactory rates of doctors and children's parents on the therapeutic effects were 57% and 63%, respectively. No adverse events, such as abdominal distention, pain or diarrhea, were observed during the treatment.
CONCLUSIONS
Cellulose is effective and safe in the treatment of functional constipation in children.
