European Journal of Medicinal Chemistry 2011-Sep
Synthesis and in-vitro anti-inflammatory activity of novel glycodendrimers with benzene 1,3,5 carboxamide core and triazole as branching unit.
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Novel glycodendrimers scaffolds containing twelve and eighteen α-D-glycopyranoside at the periphery and triazole as branching unit have been synthesized using click chemistry. Higher generation dendrimers exhibit better anti-inflammatory activity than the lower generation due to the presence of more triazole branching units and multivalent glycopyranoside units.