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Acta Cirurgica Brasileira 2016-Oct

Vertical gastrectomy in overweight and non-overweight rats.

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Fernando Issamu Tabushi
Melissa Spena Stueber
Benur Polonio
João Carlos Domingues Repka
Sérgio Ossamu Ioshii
Paulo Afonso Nunes Nassif

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Abstrak

UNASSIGNED

To compare the two lines suture (total and seromuscular) after partial gastrectomy in normal and overweight rats.

UNASSIGNED

Forty Wistar rats were distributed in two groups. Group A received normal diet; group B, normal diet and supplementation with saccharose in the water. When group B progressed to a statistically greater weight than the animals of group A, the experiment (sleeve-like gastrectomy) was conducted with gastrorraphy in two sutures lines (total and seromuscular).The animals were distributed into two subgroups of 10. A1 and A2 subgroups were sacrificed at 7 and 14 days postoperatively as well as B1 and B2. Mortality, morbidity, complications attributed to the gastric suture, biochemical dosages, Lee index, macroscopy, weight of retroperitoneal and gonadal fat, optical microscopy with hematoxylin-eosin and picrosirius-red, were the evaluation parameters.

UNASSIGNED

The overweight group achieved statistically greater weight after 16 weeks in induced obesity; there was no mortality or complications with clinical consequences attributable to morbidity. The overweight group had statistically greater weight of gonadal and retroperitoneal fat. The difference was observed in urea, albumin, total cholesterol and indirect bilirubin.

UNASSIGNED

There was no outcome difference between the overweight and non-overweight group in two suture lines in gastrorrhaphy after sleeve-like gastrectomy.

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