acetaldehyde/sakit kepala

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Determination of ALDH1b1 and ALDH2 Polymorphisms Frequency in the Brazilian Population

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According to the World Health Organization (WHO), in 2016 there were 3 million deaths worldwide from alcohol abuse. ALDH1b1 and ALDH2 proteins are involved in the alcohol metabolism promoting the conversion of acetaldehyde to acetate. The genes that encode these proteins have genetic variants, also

The Efficacy of L-cysteine in Prevention of Cluster Headache

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Background: Cluster headache belongs to a group of idiopathic headache entities, the trigeminal autonomic cephalalgias (TACs), all of which involve short-lasting, unilateral, severe headache attacks and typical accompanying autonomic symptoms. The life-time prevalence of cluster headache for adults

The Efficacy of L-cysteine in Prevention of Headache Attacks in Migraine Patients

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Background: Globally, 15% of the population is affected by migraines at some point in their life-time. Pprophylactic treatment of migraines is an important part of the total management of migraine patients, having twofold goals: i) to reduce the frequency, painfulness, and/or duration of migraines,

Interaction Between a Natural Aldehyde Dehydrogenase 2 (ALDH2) Inhibitor and Alcohol

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Soybeans contain isoflavones, which are biologically active polyphenols known as antioxidants and phytoestrogens. These isoflavones include daidzin, daidzein, genistin and glycitin, and have been implicated in the beneficial effects of soy consumption. Daidzin and daidzein are isoflavones contained

Phase IIa Study of Fomepizole for Acetaldehyde Toxicity After Ethanol Exposure in Subjects With Altered Ethanol Metabolism

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Approximately 32 subjects will be enrolled in ascending dosing cohorts of 8 subjects each. Each subject will receive an oral dose of study drug (fomepizole or placebo) with concomitant ethanol with group assignment in a randomized 1:1:1:1 ratio (2 subjects each group) on Study Day 1. Each subject is

Effect of Glutathione on Blood Alcohol and Hangover Symptoms

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Type of Study: Double-blinded control Population: 100 males Inclusion Criteria: - Males 20-40 years - Healthy, without chronic diseases, especially must have normal hepatic function, measured by serum SGPT - No history of alcoholic allergy - Drink alcohol regularly, at least once a week - Agree to

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