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acetylcysteine/nekrosis
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Pilon Fracture With Intra-articular Injection of N-Acetylcysteine (Pilon NAC)
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APAP Hepatotoxicity After Therapeutic Doses
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Paracetamol (acetaminophen, APAP) is a ubiquitous painkiller and antipyretic available worldwide in numerous over-the-counter and prescription medications. At supra-therapeutic doses, APAP is a well described hepatotoxic agent and a significant public health concern since 30'000 hospitalizations are
RIPE vs RIPE Plus N-acetylcysteine in Patients With HIV/TB Co-infection
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TB and AIDS are also diseases that occur with a chronic inflammatory stimulus, with constant formation of excessive free radicals, leading to cellular and systemic oxidative stress. The effects of NAC in both populations are studied. A study demonstrated that HIV-positive individuals have low levels
Comparison of Bovine Colostrum Versus Placebo in Treatment of Severe Alcoholic Hepatitis: A Randomized Double Blind Controlled Trial
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Diagnosis: The diagnosis of Alcoholic hepatitis is made by the following criteria (12)
I. Chronic active alcohol abuse - >80 grams in males and > 60 grams in females for > 5 years for developing Alcoholic Cirrhosis (13) Alcohol use will be evaluated with the AUDIT score (EASL guidelines (14) II.
Efficacy of Combination Therapy of Glucocorticoids and Bovine Colostrum in Treatment of Severe Alcoholic Hepatitis.
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Severe alcoholic hepatitis is associated with significant morbidity and mortality.
Diagnosis: The diagnosis of (AH) is made by the following criteria11
I.Chronic active alcohol abuse - > 80 grams in males and > 20 grams in females. II. Duration of jaundice < 3 months III. Serum Bilirubin >5 mg/dl
Sodium Bicarbonate and N-Acetylcysteine for Nephroprotection in Acute Myocardial Infarction
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Introduction Contrast-induced nephropathy (CIN) represents a potential complication of diagnostic and therapeutic procedures in interventional cardiology. In the setting of elective procedures, the strategy of sodium bicarbonate (NaHCO3) and N-acetylcysteine (NAC) infusion has been shown to reduce
Compare Methadone Combined With N-Acetyl-Cysteine (NAC) and Methadone Alone for Opioids Astaining
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Material abuse nowadays become a serious public health issue, among these, abusing of opioids is the most serious one. It cause HIV infection rate hiking up, recent years in Taiwan, it impairing people health as well. The successive 2 year methadone substitutive abstaining program makes HIV
Efficacy of N-Acetylcysteine in Prevention of Post-Catheterization Contrast-Induced Nephropathy in Diabetic Patients With Chronic Kidney Disease
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- Contrast-induced nephropathy (CIN) is the third most common cause of hospital acquired acute kidney injury, accounting for 10% of all cases. Nevertheless, use of radiocontrast media has been associated with increased in-hospital morbidity, mortality, and costs of medical care, long admission,
N-Acetylcysteine and Arginine Administration in Diabetic Patients
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Mechanisms for the Effect of Acetylcysteine on Renal Function After Exposure to Radiographic Contrast Material
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In this study we will test the hypothesis that acetylcysteine exerts a renoprotective effect in RCIN by an antioxidant and/or renal vasodilator mechanism.
We will take a structured 4-part approach, using randomised controlled cross-over studies to assess the effect of acetylcysteine on renal
The Occurence of Inflammation and Oxidative Stress in Lung Diseases
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Interstitial lung diseases (ILD) include various chronic lung disorders such as sarcoidosis and idiopathic lung fibrosis (IPF). In the Netherlands the incidence of sarcoidosis is approximately 20-25 per 100.000 inhabitants whereas that of IPF is approximately 1000-1500 new cases each year.
In short,
High-Dose N-Acetylcysteine in Cardiac Surgery
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Background
Renal impairment following cardiopulmonary bypass is common. 11.4% (1) to 42% (2) of patients with previously normal renal function show a postoperative rise in serum creatinine. While most of these patients do not require either short or long term renal replacement, the mortality of
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