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Impairment of antidiuretic hormone and atrial natriuretic peptide regulation in the obese woman with a swelling syndrome and an increase in capillary permeability to albumin.
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OBJECTIVE
To study the regulation of antidiuretic hormone (ADH) and atrial natriuretic peptide (ANP) in obese and lean women with a swelling syndrome.
METHODS
Thirty-four obese women and 12 lean women with a swelling syndrome and an abnormal isotopic test of capillary permeability to albumin were
Extra cellular water and increase in capillary permeability to albumin in overweight women with swelling syndrome.
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OBJECTIVE
To evaluate extracellular water (ECW) in the recumbent and the upright position, in overweight and lean women with swelling syndrome, and to correlate the excess in ECW with an increase in capillary filtration of albumin (CFA).
METHODS
Fifty-one women with a swelling syndrome were
Interaction of obesity and central obesity on elevated urinary albumin-to-creatinine ratio.
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BACKGROUND
Microalbuminuria was much more common among obese individuals indicating a probable association with obesity. However, association of microalbuminuria with interaction between obesity and central obesity has not yet been studied.
METHODS
A cross-sectional study was conducted in a 2889
Does Glycated Albumin Increase with Body Weight Reduction in Obese Non-Diabetic Subjects?
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We reported that the body mass index (BMI) may exert a negative effect on glycated albumin (GA) in non-diabetic subjects and patients with type 2 diabetes mellitus. In addition, we suggested a mechanism in which chronic inflammation in obesity may enhance albumin catabolism, leading to a decrease in
Obesity is an independent determinant of ischemia-modified albumin.
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OBJECTIVE
We have measured ischemia-modified albumin (IMA), total antioxidant status (TAS), total oxidant status (TOS) and high-sensitivity C-reactive protein (hsCRP) levels in obese and normal-weight subjects to investigate if IMA can be used as a biomarker of oxidative stress and inflammation and
Development of a neuromedin U-human serum albumin conjugate as a long-acting candidate for the treatment of obesity and diabetes. Comparison with the PEGylated peptide.
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Neuromedin U (NMU) is an endogenous peptide implicated in the regulation of feeding, energy homeostasis, and glycemic control, which is being considered for the therapy of obesity and diabetes. A key liability of NMU as a therapeutic is its very short half-life in vivo. We show here that conjugation
Obesity and changes in urine albumin/creatinine ratio in patients with type 2 diabetes: the DEMAND study.
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OBJECTIVE
Obesity is a potential risk factor for renal disease in non-diabetic subjects. It remains unclear whether this also applies to diabetic patients. We investigated whether obesity predicted changes in albumin excretion rate in individuals with type 2 diabetes.
RESULTS
Fifty Italian diabetes
Urinary albumin excretion is independently associated with C-reactive protein levels in overweight and obese nondiabetic premenopausal women.
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OBJECTIVE
C-reactive protein (CRP) and microalbuminuria are nowadays considered markers of chronic inflammation of the arterial wall and of endothelial dysfunction, respectively. An increase of CRP levels and of urinary albumin excretion (UAE) rate have both been reported to be independently
[Correlative study of erythrocyte membrane insulin receptor with blood lipids and albumin in non-obese noninsulin-dependent diabetics (NIDDM) patients before and after exercise].
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To understand the effects of the levels of blood lipids and albumin on insulin receptor binding before and after acute exercise, we measured insulin binding to erythrocyt membrane before and after 30 minutes moderate exercise in thirty-eight non-obese noninsulin-dependent diabetics (NIDDM) and
Urinary albumin excretion and heart rate variability in obese women.
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OBJECTIVE
The aim of this work was to examine the relationship between cardiac autonomic function and urinary albumin excretion in obesity.
METHODS
These were 27 obese non-diabetic postmenopausal women and 18 non-obese healthy postmenopausal women.
METHODS
Urinary albumin excretion as well as plasma
Prevalence and factors related to urinary albumin excretion in obese youths.
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OBJECTIVE
The aim of the present study is to assess whether obesity is associated with urinary albumin excretion and what the main determinants are.
METHODS
One hundred and thirty-four obese white children and adolescents of both sexes, ranging from 9 to 18 years of age (mean age 12.6 ± 2.0), were
Ischemia-modified albumin as an oxidative stress biomarker in obesity.
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OBJECTIVE
We evaluated the levels of ischemia-modified albumin (IMA) and its association with body mass index (BMI) in patients who are obese.
METHODS
Fasting glucose, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, malondialdehyde, and IMA levels were assessed in 148
Screening for type 2 diabetes and prediabetes in obese youth: evaluating alternate markers of glycemia - 1,5-anhydroglucitol, fructosamine, and glycated albumin.
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Hemoglobin A1c (HbA1c) is increasingly performed over the oral glucose tolerance test (OGTT) as the initial screening test for type 2 diabetes in youth. However, the optimal strategy for identifying type 2 diabetes in youth remains controversial. Alternate glycemic markers have been proposed as
Urinary Albumin Excretion, Estimated Glomerular Filtration Rate, and Prevalence of Microalbuminuria in Obese Nondiabetic and Nonhypertensive Adults: A Cross-Sectional Study.
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Urinary albumin excretion rate (AER) in newly-diagnosed type 2 Indian diabetic patients is associated with central obesity and hyperglycaemia.
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Urinary albumin excretion rate (AER) was measured in non-diabetic controls (n = 143) and newly diagnosed impaired glucose tolerant (IGT, n = 64) and non-insulin-dependent (type 2) diabetic patients (n = 146). AER progressively increased from non-diabetic [3.7 (1.1-51.3) micrograms/min, median
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