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Antimalarial, antiplasmodial and analgesic activities of root extract of Alchornea laxiflora.
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BACKGROUND
Alchornea laxiflora (Benth.) Pax. & Hoffman (Euphorbiaceae) root decoctions are traditionally used in the treatment of malaria and pain in Nigeria.
OBJECTIVE
To assess the antimalarial, antiplasmodial and analgesic potentials of root extract and fractions against malarial infections and
Anti-inflammatory effects of crude methanolic extract and fractions of Alchornea cordifolia leaves.
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The leaves of Alchornea cordifolia were collected, identified, dried, and reduced to coarse powder and extracted with aqueous methanol. Using various solvent treatments, the powdered dried leaf was fractionated into five fractions, A1, A2, B, C, D and E. The fractions were subjected to phytochemical
Acetaminophen-induced liver damage in mice: effects of some medicinal plants on the oxidative defense system.
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Paracetamol (acetaminophen, PCM) is widely used as an over-the-counter analgesic and antipyretic drug. Intake of a large dose of PCM may result in severe hepatic necrosis. Oxidative stress mediated by oxidative capacities of the PCM metabolite (N-acetyl-p-benzoquinoneimine (NAPQI), is considered as
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